Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN7 | P35236 | 5/20 | 0.61 |
| ▸ | HMGCR | P04035 | 3/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | RECQL | P46063 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11795105 | 0.98 | PTPN7 (0.64) | PTPN7HMGCRMAPTRECQLTDP1 | |
| SCHEMBL11525743 | 0.93 | PTPN7 (0.53) | PTPN7HMGCRMAPTRECQLTDP1 | |
| SCHEMBL21682850 | 0.88 | PTPN7 (0.74) | PTPN7HMGCRMAPTRECQLTDP1 | |
| SCHEMBL196242 | 0.85 | PTPN7 (0.78) | PTPN7HMGCRMAPTRECQLTDP1 | |
| SCHEMBL22540045 | 0.85 | PTPN7 (0.78) | PTPN7HMGCRMAPTRECQLTDP1 | |
| SCHEMBL196457 | 0.85 | PTPN7 (0.78) | PTPN7HMGCRMAPTRECQLTDP1 | |
| SCHEMBL4972624 | 0.83 | PTPN7 (0.68) | PTPN7HMGCRMAPTRECQLTDP1 | |
| SCHEMBL28386570 | 0.81 | PTPN7 (0.72) | PTPN7HMGCRMAPTRECQLTDP1 | |
| SCHEMBL29574312 | 0.81 | PTPN7 (0.72) | PTPN7HMGCRMAPTRECQLTDP1 | |
| SCHEMBL11211890 | 0.80 | PTPN7 (0.44) | PTPN7HMGCRMAPTRECQLTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4355170-A | ANTIINFLAMMATORY, HYPERTENSIVE, ANTIASTHMATIC AGENTS, A THROMBOXANE SYNTHETASE INHIBITORS | ONO PHARMACEUTICAL CO., LTD. (JP) | 1982-10-19 | — | — | US | disclosed |
| US-4256757-A | ANTIINFLAMMATORY AND HYPOTENSIVE AGENTS; THROMBOSIS; ASTHMA; NERVOUS SYSTEM DISORDERS | ONO PHARMACEUTICAL CO., LTD. | 1981-03-17 | — | — | US | disclosed |