Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.46 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.42 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.42 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | PRKCZ | Q05513 | 2/20 | 0.40 |
| ▸ | PRKCI | P41743 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11262182 | 0.85 | NPC1 (0.50) | MAPTHSD17B10NPC1MAPK1RAB9A | |
| SCHEMBL11283228 | 0.84 | MAPT (0.49) | MAPTHSD17B10NPC1MAPK1RAB9A | |
| Hydrochloric Acid SCHEMBL11283231 | 0.84 | NPC1 (0.49) | MAPTHSD17B10NPC1MAPK1RAB9A | |
| SCHEMBL11278824 | 0.80 | HTT (0.52) | MAPTHSD17B10NPC1MAPK1RAB9A | |
| SCHEMBL11264741 | 0.78 | FGFR1 (0.43) | MAPTHSD17B10NPC1MAPK1RAB9A | |
| SCHEMBL11264995 | 0.70 | ALDH1A1 (0.47) | MAPTHSD17B10NPC1MAPK1RAB9A | |
| SCHEMBL11281901 | 0.69 | NR4A2 (0.52) | MAPTHSD17B10NPC1MAPK1RAB9A | |
| SCHEMBL23300917 | 0.67 | CTNNB1 (0.44) | HSD17B10MAPK1RECQLALDH1A1HPGD | |
| SCHEMBL29831483 | 0.67 | CTNNB1 (0.44) | HSD17B10MAPK1RECQLALDH1A1HPGD | |
| SCHEMBL13837654 | 0.67 | MAPT (0.77) | MAPTHSD17B10MAPK1BRD4BRD9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4364956-A | ASTHMA | LILLY INDUSTRIES LIMITED (GB) | 1982-12-21 | — | — | US | disclosed |