Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | NOS1 | P29475 | 2/20 | 0.35 |
| ▸ | NOS2 | P35228 | 2/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.34 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.34 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.34 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | GBA1 | P04062 | 3/20 | 0.33 |
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31621901 | 1.00 | TSHR (0.46) | TSHRHTTSMN1; SMN2CYP1A2NOS1 | |
| SCHEMBL28122037 | 0.98 | SMN1; SMN2 (0.43) | TSHRHTTSMN1; SMN2CYP1A2NOS1 | |
| SCHEMBL16268882 | 0.95 | TSHR (0.47) | TSHRHTTSMN1; SMN2CYP1A2EPHX1 | |
| SCHEMBL7631294 | 0.95 | TSHR (0.47) | TSHRHTTSMN1; SMN2CYP1A2EPHX1 | |
| SCHEMBL17702652 | 0.95 | TSHR (0.47) | TSHRHTTSMN1; SMN2CYP1A2EPHX1 | |
| SCHEMBL7624114 | 0.95 | TSHR (0.47) | TSHRHTTSMN1; SMN2CYP1A2EPHX1 | |
| SCHEMBL16268462 | 0.93 | HTT (0.44) | TSHRHTTSMN1; SMN2CYP1A2EPHX1 | |
| SCHEMBL11154919 | 0.93 | NOS1 (0.40) | TSHRHTTSMN1; SMN2CYP1A2NOS1 | |
| SCHEMBL16274089 | 0.93 | HTT (0.44) | TSHRHTTSMN1; SMN2CYP1A2EPHX1 | |
| SCHEMBL11154190 | 0.93 | NOS1 (0.40) | TSHRHTTSMN1; SMN2CYP1A2NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0016446-B1 | PROCESS FOR THE PREPARATION OF O,N-DISUBSTITUTED HYDROXYL AMINES | BASF Aktiengesellschaft (DE) | 1982-06-02 | — | — | EP | disclosed |
| US-4260562-A | HYDROGENATION OF A KETOXIME, PLATINUM, MINERAL ACID | BASF AKTIENGESELLSCHAFT (DE) | 1981-04-07 | — | — | US | disclosed |