Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8596838 | 0.98 | HSD17B10 (0.31) | HSD17B10KDM4EHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL11628007 | 0.90 | — | — | |
| SCHEMBL8596835 | 0.85 | HSD17B10 (0.31) | HSD17B10KDM4EHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL22661231 | 0.84 | MEN1 (0.32) | HSD17B10ALDH1A1 | |
| Hydrochloric Acid SCHEMBL11279952 | 0.83 | MEN1 (0.31) | HSD17B10ALDH1A1 | |
| SCHEMBL11633157 | 0.80 | — | — | |
| SCHEMBL11630049 | 0.79 | MAPK1 (0.41) | HSD17B10KDM4ESMN1; SMN2ALDH1A1CYP1A2 | |
| SCHEMBL8948812 | 0.77 | TSHR (0.43) | HPGDALDH1A1MAPT | |
| SCHEMBL11631808 | 0.77 | — | — | |
| SCHEMBL11633284 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4364921-A | RADIOPACITY | SCHERING, AKTIENGESELLSCHAFT (DE) | 1982-12-21 | — | — | US | disclosed |