Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | KDM5A | P29375 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | LTA4H | P09960 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8948721 | 0.85 | SLC22A6 (0.35) | TSHRKDM5ALMNA | |
| SCHEMBL11632881 | 0.82 | SLC22A6 (0.35) | TSHRKDM5ALMNA | |
| SCHEMBL11631931 | 0.77 | MEN1 (0.45) | TSHRMEN1KMT2AL3MBTL1LMNA | |
| SCHEMBL11275798 | 0.77 | HSD17B10 (0.32) | ALDH1A1MAPTHPGD | |
| SCHEMBL11635038 | 0.77 | LMNA (0.32) | LMNA | |
| SCHEMBL11635913 | 0.76 | PHF8 (0.31) | — | |
| SCHEMBL11631451 | 0.75 | TSHR (0.45) | TSHRMEN1KMT2AMAPTL3MBTL1 | |
| SCHEMBL11630537 | 0.74 | TSHR (0.44) | TSHRMEN1KMT2AMAPTHPGD | |
| SCHEMBL8948705 | 0.74 | MEN1 (0.56) | TSHRMEN1KMT2AMAPTL3MBTL1 | |
| SCHEMBL11634546 | 0.73 | LMNA (0.51) | KDM5ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5569446-A | Radiohalogenation of proteins using trihalophenyl derivatives | BRACCO INTERNATIONAL B.V. | 1996-10-29 | — | — | US | disclosed |
| US-5463080-A | 2,4,6-triiodo-1,3-benzenedicarboxylic acid compounds used as radiolabelling reagents | BRACCO INTERNATIONAL B.V. (NL) | 1995-10-31 | — | — | US | disclosed |