SCHEMBL1127590

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1127361	0.89	CYP1A2 (0.53)	NPSR1CYP2D6TSHRP4HTMCYP1A2
	SCHEMBL3373228	0.87	KMT2A (0.45)	KMT2ABLMLMNAPMP22NPSR1
	SCHEMBL1127707	0.82	KMT2A (0.52)	KMT2ABLMLMNAPMP22NPSR1
	SCHEMBL1127294	0.82	MME (0.41)	NPSR1PPARGP4HTMMMECYP1A2
	SCHEMBL1127419	0.81	KDM4E (0.42)	KMT2ASLC6A2P4HTMCYP1A2
	SCHEMBL1127390	0.79	KMT2A (0.48)	KMT2ABLMLMNAPMP22NPSR1
	SCHEMBL1127686	0.78	PTPRA (0.41)	NPSR1PPARGPPARASLC6A2SLC6A4
	SCHEMBL3370947	0.78	EPHX1 (0.56)	PPARGPPARACYP2C9P4HTMPOLB
	SCHEMBL2583959	0.78	CYP1A2 (0.47)	KMT2ALMNANPSR1SLC6A2SLC6A4
	SCHEMBL1127394	0.78	MME (0.39)	KMT2ABLMLMNAPMP22NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.