HDGF

Hepatoma-derived growth factor · P51858 · HDGF on Sugi Atlas →

0 patent compounds predicted against HDGF, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to HDGF by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Radiofrequency Ablation Versus Hepatic Resection for the Treatment of Hepatocellular Carcinomas Smaller Than 2 cm PHASE4UNKNOWN
Study of IMC-1121B (Ramucirumab) in Participants With Liver Cancer Who Have Not Previously Been Treated With Chemotherapy PHASE2COMPLETED
Phase I/II Study of Recombinant Human Hepatocyte Growth Factor in Fulminant Hepatic Failure PHASE1/PHASE2UNKNOWN
A Phase Ib/II Trial to Evaluate the Efficacy and Safety of HH-009 for the Treatment of FGF19-positive Advanced or Unresectable HCC PHASE1/PHASE2RECRUITING
Bevacizumab in Treating Patients With Unresectable Nonmetastatic Liver Cancer PHASE2COMPLETED
Hepatitis B Immune Globulin (HBIg) to Restore Immune Control in People With Chronic Hepatitis B PHASE2WITHDRAWN
Sorafenib Plus Tegafur/Uracil (UFUR®) for Hepatocellular Carcinoma (HCC) PHASE2COMPLETED
Sorafenib With Capecitabine and Oxaliplatin for Advanced or Metastatic Hepatocellular Carcinoma PHASE2UNKNOWN
Sunitinib for Advanced Thymus Cancer Following Earlier Treatment PHASE2COMPLETED
Futibatinib and Pembrolizumab for Treatment of Advanced or Metastatic FGF19 Positive BCLC Stage A, B, or C Liver Cancer PHASE2COMPLETED
Resveratrol and Human Hepatocyte Function in Cancer PHASE1/PHASE2WITHDRAWN
A Phase II Study of Radiotherapy for Locally Advanced Hepatocellular Carcinoma (HCC) PHASE2COMPLETED
Branched-chain Amino Acid Supplementation for Hepatocellular Carcinoma PHASE2WITHDRAWN
A Dose Escalation Trial of Radiation Therapy (RT) for Hepatocellular Carcinoma (HCC) PHASE1UNKNOWN
Pazopanib and ARQ 197 for Advanced Solid Tumors PHASE1COMPLETED
Levels of Interleukin-6 andTransforming Growth Factor Beta in HCV Patients Sera EARLY_PHASE1UNKNOWN
A Clinical Trial for the Safety and Efficacy of CD-801 in Patients With Advanced Hepatocellular Carcinoma EARLY_PHASE1COMPLETED
VEGF Signaling Promotes Cell Growth and Metastasis in Hepatocellular Carcinoma in a VEGF Receptor Mediated Pathway nanUNKNOWN
Growth Factors and Hepatic Progenitor Cells in Acute Liver Failure nanUNKNOWN
Evaluation of Risk of hEpatocellular Carcinoma nanRECRUITING
Stromal Vascular Cells for the Treatment of Diabetic Peripheral Neuropathy nanCOMPLETED
Baker Cyst Aspiration Combined With Platelet-rich Plasma Injection in Knee Osteoarthritis nanCOMPLETED
Evaluation of the Use of Granulocyte Colony Stimulating Factor (GCSF) in Post Kasai Type 3 Biliary Atresia nanRECRUITING
Recurrence and Distant Metastases in Hepatocellular Carcinoma Treated by Transcatheter Arterial Chemoembolization nanCOMPLETED
Biomarkers in the Diagnosis and Prognosis of NAFLD nanRECRUITING
HOPE to Reduce Tumour Recurrence After LT In Patients With HCC nanUNKNOWN
Tumor Growth Factors in Hepatocellular Carcinoma nanCOMPLETED
Anti-angiogenic Targeted Drugs Plus Rg3 to Improve the Efficacy of TACE for Unresectable Hepatocellular Carcinoma nanUNKNOWN
Direct Versus Indirect Effect of Amino Acids on Hepatokines nanACTIVE_NOT_RECRUITING
Novel Biomarker Assay for Biomarker Assay for HCC Detection nanUNKNOWN

Related proteins — ESM-2 sequence neighbours (a HDGF binder may also engage these)

ProteinNameSimilarity
P51859 1.000 P51859 →
Q8VHK7 1.000 Q8VHK7 →
Q9XSK7 0.995 Q9XSK7 →
Q923W4 0.991 Q923W4 →
Q9JMG7 0.988 Q9JMG7 →
Q5TGJ6 0.986 Q5TGJ6 →
Q5XXA9 0.985 Q5XXA9 →
Q812D1 0.985 Q812D1 →
HDGFL3 Hepatoma-derived growth factor-related protein 3 0.984 landscape →
Q99JF8 0.984 Q99JF8 →
Q66T72 0.984 Q66T72 →
Q3UMU9 0.983 Q3UMU9 →
PSIP1 PC4 and SFRS1-interacting protein 0.982 landscape →
F8VPQ2 0.980 F8VPQ2 →
Q32N87 0.980 Q32N87 →
Q6P4K1 0.980 Q6P4K1 →
Q925G1 0.978 Q925G1 →
Q8MJG1 0.978 Q8MJG1 →
Q7Z4V5 0.977 Q7Z4V5 →
Q5XXA7 0.977 Q5XXA7 →
P20689 0.977 P20689 →
A6QLA6 0.976 A6QLA6 →
Q9BTC0 0.976 Q9BTC0 →
PHF20 PHD finger protein 20 0.975 landscape →
B1H224 0.975 B1H224 →
Q5VZ18 0.975 Q5VZ18 →
P48382 0.975 P48382 →
Q8CCG4 0.975 Q8CCG4 →
MYLK2 Myosin light chain kinase 2, skeletal/cardiac muscle 0.974 landscape →
Q17R10 0.974 Q17R10 →