Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Nitric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.67 |
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | TP53 | P04637 | 4/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.53 |
| ▸ | ESR1 | P03372 | 1/20 | 0.53 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.53 |
| ▸ | PGR | P06401 | 1/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.53 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.53 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nitric Acid SCHEMBL11276844 | 0.93 | L3MBTL1 (0.66) | L3MBTL1LMNATP53CYP3A4HIF1A | |
| Nitric Acid SCHEMBL11275468 | 0.92 | L3MBTL1 (0.66) | L3MBTL1LMNATP53CYP3A4HIF1A | |
| Nitric Acid SCHEMBL11303476 | 0.92 | L3MBTL1 (0.67) | L3MBTL1LMNATP53CYP3A4HIF1A | |
| SCHEMBL11274465 | 0.92 | CYP1A2 (0.61) | L3MBTL1LMNATP53CYP3A4HIF1A | |
| SCHEMBL11279489 | 0.87 | CYP1A2 (0.57) | L3MBTL1LMNATP53CYP3A4HIF1A | |
| Nitric Acid SCHEMBL11284012 | 0.86 | L3MBTL1 (0.64) | L3MBTL1LMNATP53CYP3A4HIF1A | |
| SCHEMBL11278579 | 0.85 | CYP1A2 (0.52) | L3MBTL1LMNATP53CYP3A4HIF1A | |
| Nitric Acid SCHEMBL11275785 | 0.84 | L3MBTL1 (0.59) | L3MBTL1LMNATP53CYP3A4HIF1A | |
| SCHEMBL11275963 | 0.84 | CYP1A2 (0.60) | L3MBTL1LMNATP53CYP3A4HIF1A | |
| Nitric Acid SCHEMBL11283104 | 0.84 | L3MBTL1 (0.59) | L3MBTL1LMNATP53CYP3A4HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0064244-A1 | Spermicidal 1-bis(arylalkyl)alkylimidazoles | SYNTEX (U.S.A.) INC. (US) | 1982-11-10 | — | — | EP | disclosed |