Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TBXAS1 | P24557 | 4/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11276090 | 1.00 | KMT2A (0.49) | KMT2AKDM4EL3MBTL1TBXAS1TBXA2R | |
| SCHEMBL11283342 | 0.84 | TBXAS1 (0.54) | KMT2AKDM4ETBXAS1TBXA2RTDP1 | |
| SCHEMBL11283338 | 0.84 | TBXAS1 (0.54) | KMT2AKDM4ETBXAS1TBXA2RTDP1 | |
| Hydrochloric Acid SCHEMBL11266012 | 0.83 | TBXAS1 (0.55) | KDM4ETBXAS1TBXA2RTDP1 | |
| Hydrochloric Acid SCHEMBL11266009 | 0.83 | TBXAS1 (0.55) | KDM4ETBXAS1TBXA2RTDP1 | |
| SCHEMBL15153541 | 0.83 | PPARG (0.43) | L3MBTL1TBXAS1TBXA2R | |
| SCHEMBL15153414 | 0.83 | PPARG (0.43) | L3MBTL1TBXAS1TBXA2R | |
| SCHEMBL15153359 | 0.83 | PPARG (0.43) | L3MBTL1TBXAS1TBXA2R | |
| SCHEMBL27968391 | 0.79 | KMT2A (0.59) | KMT2AKDM4EL3MBTL1ALDH1A1MAPT | |
| Bicarbonate SCHEMBL28519256 | 0.78 | KDM4E (0.49) | KMT2AKDM4ETBXAS1TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4355170-A | ANTIINFLAMMATORY, HYPERTENSIVE, ANTIASTHMATIC AGENTS, A THROMBOXANE SYNTHETASE INHIBITORS | ONO PHARMACEUTICAL CO., LTD. (JP) | 1982-10-19 | — | — | US | disclosed |
| US-4256757-A | ANTIINFLAMMATORY AND HYPOTENSIVE AGENTS; THROMBOSIS; ASTHMA; NERVOUS SYSTEM DISORDERS | ONO PHARMACEUTICAL CO., LTD. | 1981-03-17 | — | — | US | disclosed |