Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11041517 | 0.87 | GAA (0.55) | GAAALDH1A1KDM4ENPC1CDK1 | |
| SCHEMBL11042138 | 0.82 | GAA (0.48) | GAAALDH1A1KDM4ENPC1CDK1 | |
| SCHEMBL11045687 | 0.81 | GAA (0.44) | GAAALDH1A1KDM4ENPC1SMN1; SMN2 | |
| SCHEMBL11042105 | 0.80 | ALDH1A1 (0.41) | GAAALDH1A1KDM4ENPC1SMN1; SMN2 | |
| SCHEMBL11045417 | 0.80 | ALDH1A1 (0.45) | GAAALDH1A1KDM4ENPC1SMN1; SMN2 | |
| SCHEMBL11043115 | 0.76 | ALDH1A1 (0.43) | GAAALDH1A1KDM4ENPC1SMN1; SMN2 | |
| SCHEMBL11045452 | 0.74 | MAPT (0.40) | GAAALDH1A1KDM4ENPC1SMN1; SMN2 | |
| SCHEMBL11255297 | 0.74 | CDK1 (0.46) | GAAALDH1A1KDM4ENPC1CDK1 | |
| SCHEMBL11045546 | 0.74 | GAA (0.54) | GAAALDH1A1KDM4ECDK1SMN1; SMN2 | |
| SCHEMBL10937189 | 0.72 | GAA (0.52) | GAACDK1TP53GLAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0057546-A2 | Sulfonylurea N-oxides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-08-11 | — | — | EP | claimed |
| EP-0057546-A2 | Sulfonylurea N-oxides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-08-11 | — | — | EP | disclosed |