SCHEMBL11276208

SCHEMBL11276208

COc1ccc(CCC(Cc2ccccc2)Cn2ccnc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.54
CYP3A4 P08684 2/20 0.54
MAPT P10636 2/20 0.54
TDP1 Q9NUW8 2/20 0.54
MAPK1 P28482 2/20 0.54
MEN1 O00255 1/20 0.54
TP53 P04637 1/20 0.54
CYP1A2 P05177 1/20 0.54
TSHR P16473 1/20 0.54
KMT2A Q03164 1/20 0.54
HSD17B10 Q99714 1/20 0.54
CYP2C9 P11712 1/20 0.54
SMN1; SMN2 Q16637 1/20 0.54
TRPM8 Q7Z2W7 1/20 0.54
ORAI1 Q96D31 1/20 0.53
CYP19A1 P11511 4/20 0.52
TBXAS1 P24557 7/20 0.51
HMOX1 P09601 1/20 0.49
GAA P10253 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11278157 0.94 ALDH1A1 (0.57) ALDH1A1CYP3A4MAPTTDP1MAPK1
SCHEMBL11285064 0.92 CYP19A1 (0.57) ALDH1A1CYP3A4MAPTTDP1MAPK1
SCHEMBL11284177 0.91 CYP3A4 (0.54) ALDH1A1CYP3A4MAPTTDP1MAPK1
SCHEMBL11273603 0.90 IDO1 (0.53) ALDH1A1CYP3A4MAPTTDP1MAPK1
SCHEMBL11304071 0.89 CYP19A1 (0.53) CYP3A4MAPTCYP1A2CYP19A1TBXAS1
SCHEMBL11279593 0.88 ALDH1A1 (0.51) ALDH1A1CYP3A4MAPTTDP1MAPK1
SCHEMBL11287493 0.87 CYP19A1 (0.50) CYP3A4MAPTCYP1A2CYP19A1TBXAS1
SCHEMBL11276748 0.87 CYP19A1 (0.50) CYP3A4MAPTCYP1A2CYP19A1TBXAS1
SCHEMBL11277068 0.87 ALDH1A1 (0.50) ALDH1A1CYP3A4MAPTTDP1MAPK1
SCHEMBL11276103 0.84 CYP1A2 (0.57) ALDH1A1CYP3A4MAPTTDP1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0064244-A1 Spermicidal 1-bis(arylalkyl)alkylimidazoles SYNTEX (U.S.A.) INC. (US) 1982-11-10 EP disclosed