Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | BCL9 | O00512 | 1/20 | 0.42 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | FBP1 | P09467 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HRH2 | P25021 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11281302 | 0.84 | ALDH1A1 (0.44) | MAPTL3MBTL1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL11271227 | 0.83 | ALDH1A1 (0.41) | MAPTL3MBTL1HTR2AKMT2AMEN1 | |
| SCHEMBL11271870 | 0.83 | ALDH1A1 (0.43) | MAPTL3MBTL1HTR2AKMT2AMEN1 | |
| SCHEMBL11272661 | 0.82 | PPARA (0.56) | MAPTHTR2AKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL11285398 | 0.82 | CYP1A2 (0.40) | MAPTHTR2AKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL11513529 | 0.82 | MAPT (0.50) | MAPTHTR2AKMT2ABCL9CTNNB1 | |
| SCHEMBL11266219 | 0.81 | MAPT (0.47) | MAPTL3MBTL1SMN1; SMN2LMNAPKM | |
| SCHEMBL11539226 | 0.81 | HTR2A (0.43) | MAPTCRHBPCRHR2L3MBTL1HTR2A | |
| SCHEMBL11277557 | 0.80 | PPARA (0.53) | MAPTHTR2AKMT2AMEN1ALDH1A1 | |
| SCHEMBL11271624 | 0.80 | SMN1; SMN2 (0.47) | MAPTL3MBTL1HTR2AKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4331674-A | Combating fungi with 4-phenoxy-4-(azolyl-1-yl)-butanoic acid derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1982-05-25 | — | — | US | disclosed |