Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 13/20 | 0.57 |
| ▸ | SPHK2 | Q9NRA0 | 7/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11279119 | 1.00 | SPHK1 (0.57) | SPHK1SPHK2MAPTGAACYP2C9 | |
| SCHEMBL11276529 | 1.00 | SPHK1 (0.57) | SPHK1SPHK2MAPTGAACYP2C9 | |
| SCHEMBL11283046 | 1.00 | SPHK1 (0.57) | SPHK1SPHK2MAPTGAACYP2C9 | |
| SCHEMBL11278870 | 1.00 | SPHK1 (0.57) | SPHK1SPHK2MAPTGAACYP2C9 | |
| SCHEMBL11271469 | 1.00 | SPHK1 (0.57) | SPHK1SPHK2MAPTGAACYP2C9 | |
| SCHEMBL11283112 | 1.00 | SPHK1 (0.57) | SPHK1SPHK2MAPTGAACYP2C9 | |
| SCHEMBL11277627 | 0.99 | SPHK1 (0.55) | SPHK1SPHK2MAPTGAACYP2C9 | |
| SCHEMBL8522462 | 0.97 | SPHK1 (0.54) | SPHK1SPHK2MAPTGAACYP2C9 | |
| SCHEMBL8083689 | 0.97 | SPHK1 (0.54) | SPHK1SPHK2MAPTGAACYP2C9 | |
| SCHEMBL21084420 | 0.96 | SPHK1 (0.61) | SPHK1SPHK2MAPTGAACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0022183-B1 | DERIVATIVES OF CYCLOHEXYLBIPHENYL, PROCESS FOR THEIR PREPARATION, DIELECTRICS CONTAINING THEM, AND ELECTRON OPTICAL INDICATING ELEMENTS | MERCK PATENT GmbH (DE) | 1982-06-23 | — | — | EP | disclosed |
| US-4330426-A | Cyclohexylbiphenyls, their preparation and use in dielectrics and electrooptical display elements | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1982-05-18 | — | — | US | disclosed |
| EP-0022183-A2 | Derivatives of cyclohexylbiphenyl, process for their preparation, dielectrics containing them, and electron optical indicating elements | MERCK PATENT GmbH (DE) | 1981-01-14 | — | — | EP | disclosed |