SCHEMBL8083689

SCHEMBL8083689

CCCCCC1CCC(c2ccc(-c3ccc(CCc4ccc(CCC)cc4)cc3)cc2)CC1

nearest known ligand 0.54

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
SPHK1 Q9NYA1 13/20 0.54
SPHK2 Q9NRA0 7/20 0.47
CYP2C9 P11712 1/20 0.43
MAPT P10636 2/20 0.41
ALDH1A1 P00352 1/20 0.41
LMNA P02545 1/20 0.41
MEN1 O00255 1/20 0.41
MAPK1 P28482 1/20 0.41
KMT2A Q03164 1/20 0.41
GAA P10253 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8522462 1.00 SPHK1 (0.54) SPHK1SPHK2CYP2C9MAPTALDH1A1
SCHEMBL11277627 0.99 SPHK1 (0.55) SPHK1SPHK2CYP2C9MAPTALDH1A1
SCHEMBL11276348 0.97 SPHK1 (0.57) SPHK1SPHK2CYP2C9MAPTALDH1A1
SCHEMBL11283112 0.97 SPHK1 (0.57) SPHK1SPHK2CYP2C9MAPTALDH1A1
SCHEMBL11283046 0.97 SPHK1 (0.57) SPHK1SPHK2CYP2C9MAPTALDH1A1
SCHEMBL11276529 0.97 SPHK1 (0.57) SPHK1SPHK2CYP2C9MAPTALDH1A1
SCHEMBL11278870 0.97 SPHK1 (0.57) SPHK1SPHK2CYP2C9MAPTALDH1A1
SCHEMBL11279119 0.97 SPHK1 (0.57) SPHK1SPHK2CYP2C9MAPTALDH1A1
SCHEMBL11271469 0.97 SPHK1 (0.57) SPHK1SPHK2CYP2C9MAPTALDH1A1
SCHEMBL10790504 0.97 SPHK1 (0.56) SPHK1SPHK2CYP2C9MAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0805134-B1 NOVEL LIQUID-CRYSTAL COMPOUNDS BEARING DIENYL MOIETY AND LIQUID-CRYSTAL COMPOSITION CHISSO CORP (JP) 2000-08-30 EP disclosed
EP-0679707-B1 Liquid crystalline compound, liquid crystal composition and liquid crystal display element CHISSO CORP (JP) 1999-06-16 EP disclosed
US-5720899-A Liquid crystalline compound, liquid crystal composition and liquid crystal display element CHISSO CORPORATION (JP) 1998-02-24 US disclosed
CN-1169138-A Novel liquid crystal compound bearing dienyl moiety and liquid crystal composition CHISSO CORP (JP) 1997-12-31 CN disclosed
EP-0805134-A1 NOVEL LIQUID-CRYSTAL COMPOUNDS BEARING DIENYL MOIETY AND LIQUID-CRYSTAL COMPOSITION CHISSO CORPORATION (JP) 1997-11-05 EP disclosed
US-5653911-A Liquid crystalline compound liquid crystal composition and liquid crystal display element CHISSO CORPORATION (JP) 1997-08-05 US disclosed
EP-0679707-A1 Liquid crystalline compound, liquid crystal composition and liquid crystal display element Chisso Corporation (JP) 1995-11-02 EP disclosed