Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPG | P10696 | 1/20 | 0.42 |
| ▸ | PTAFR | P25105 | 7/20 | 0.41 |
| ▸ | TBXAS1 | P24557 | 10/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11279272 | 0.87 | ALPG (0.45) | ALPGPTAFRTBXAS1CTDSP1KDM4E | |
| SCHEMBL11277337 | 0.83 | ALPG (0.63) | ALPGPTAFRTBXAS1KDM4EALDH1A1 | |
| SCHEMBL11270196 | 0.82 | PTAFR (0.55) | PTAFRTBXAS1 | |
| Hydrochloric Acid SCHEMBL11263594 | 0.77 | ALPG (0.67) | ALPGPTAFRTBXAS1KDM4EMEN1 | |
| SCHEMBL11260665 | 0.75 | ALPG (0.36) | ALPGPTAFRTBXAS1KDM4EALDH1A1 | |
| Benzoic Acid SCHEMBL11271905 | 0.74 | ALPG (0.57) | ALPGPTAFRTBXAS1CTDSP1KDM4E | |
| Benzoic Acid SCHEMBL11267397 | 0.71 | ALPG (0.71) | ALPGPTAFRTBXAS1CTDSP1KDM4E | |
| SCHEMBL11265853 | 0.69 | ALPG (0.60) | ALPGPTAFRTBXAS1CTDSP1KDM4E | |
| SCHEMBL11270745 | 0.69 | ALPG (0.67) | ALPGPTAFRTBXAS1CTDSP1KDM4E | |
| SCHEMBL11083308 | 0.69 | AKR1C3 (0.53) | ALPGPTAFRTBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4348396-A | Substituted 11-oxo-11H-pyrido[2,1-b]quinazolines and method of inhibiting allergic reactions with them | HOFFMANN-LA ROCHE INC. (US) | 1982-09-07 | — | — | US | disclosed |