Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.38 |
| ▸ | SPHK1 | Q9NYA1 | 3/20 | 0.37 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.36 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 3/20 | 0.35 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11281791 | 0.96 | MAPT (0.42) | ALDH1A1LMNAMAPTCYP2C9MEN1 | |
| SCHEMBL11286749 | 0.95 | MAPT (0.41) | ALDH1A1LMNAMAPTCYP2C9MEN1 | |
| SCHEMBL11284312 | 0.95 | MAPT (0.41) | ALDH1A1LMNAMAPTCYP2C9MEN1 | |
| SCHEMBL11278285 | 0.95 | MAPT (0.41) | ALDH1A1LMNAMAPTCYP2C9MEN1 | |
| SCHEMBL11286048 | 0.95 | MAPT (0.41) | ALDH1A1LMNAMAPTCYP2C9MEN1 | |
| SCHEMBL11272083 | 0.95 | MAPT (0.41) | ALDH1A1LMNAMAPTCYP2C9MEN1 | |
| SCHEMBL11274726 | 0.92 | ALDH1A1 (0.41) | ALDH1A1LMNAMAPTCYP2C9MEN1 | |
| SCHEMBL11285293 | 0.92 | MAPT (0.41) | ALDH1A1LMNAMAPTCYP2C9MEN1 | |
| SCHEMBL11284298 | 0.92 | ALDH1A1 (0.51) | ALDH1A1LMNAMAPTCYP2C9MEN1 | |
| SCHEMBL11275636 | 0.91 | MAPT (0.40) | ALDH1A1LMNAMAPTCYP2C9MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4330426-A | Cyclohexylbiphenyls, their preparation and use in dielectrics and electrooptical display elements | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1982-05-18 | — | — | US | disclosed |