SCHEMBL1127682

SCHEMBL1127682

C=C(CCCNC)C(N)=O.COS(=O)(=O)O

nearest known ligand 0.30

Known targets — ChEMBL curated mechanism

ACHECHRM1CHRM3

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.30
CA14 Q9ULX7 2/20 0.30
CA2 P00918 1/20 0.30
CA7 P43166 1/20 0.30
CA9 Q16790 1/20 0.30
KDM4A O75164 1/20 0.30
KDM4C Q9H3R0 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4449313 0.86 TDP1 (0.35) KDM4AKDM4C
SCHEMBL8527958 0.85 KDM4A (0.34) CA12CA14CA2CA7CA9
SCHEMBL15846863 0.84 KDM4A (0.40) KDM4AKDM4C
SCHEMBL15846310 0.78 ALDH1A1 (0.32) CA12CA14CA2CA7CA9
SCHEMBL2066066 0.77 PAOX (0.33)
Trimethylammonium SCHEMBL1232296 0.77 ALDH1A1 (0.36) CA12CA14CA2CA7CA9
Water SCHEMBL28392635 0.76 PAOX (0.32)
SCHEMBL1507142 0.74
SCHEMBL28029114 0.73 GSR (0.32)
Trimethylammonium SCHEMBL27920518 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2282716-A2 DELIVERY OF HYDROPHOBIC BENEFIT AGENTS FROM BODYWASHES AND THE LIKE ONTO A KERATINOUS SUBSTRATE BASF SE (DE) 2011-02-16 EP disclosed
WO-2009130144-A2 DELIVERY OF HYDROPHOBIC BENEFIT AGENTS FROM BODYWASHES AND THE LIKE ONTO A KERATINOUS SUBSTRATE BASF SE (DE) 2009-10-29 WO disclosed