Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | RXRB | P28702 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29673223 | 0.83 | KMT2A (0.50) | KMT2ARAD52RXFP1GAAALDH1A1 | |
| SCHEMBL7410245 | 0.83 | KMT2A (0.50) | KMT2ARAD52RXFP1GAAALDH1A1 | |
| Hydrochloric Acid SCHEMBL5957935 | 0.81 | KMT2A (0.53) | KMT2ARAD52RXFP1GAAALDH1A1 | |
| SCHEMBL5504129 | 0.81 | KMT2A (0.47) | KMT2ARAD52RXFP1GAAALDH1A1 | |
| Hydrochloric Acid SCHEMBL5957846 | 0.79 | KMT2A (0.50) | KMT2ARAD52RXFP1GAAALDH1A1 | |
| SCHEMBL5957796 | 0.79 | KMT2A (0.46) | KMT2ARAD52RXFP1GAAALDH1A1 | |
| Hydrochloric Acid SCHEMBL6259121 | 0.77 | KMT2A (0.48) | KMT2ARAD52RXFP1GAAALDH1A1 | |
| SCHEMBL12430513 | 0.73 | NPC1 (0.42) | KMT2AALDH1A1TP53MEN1HTT | |
| SCHEMBL12430501 | 0.73 | METAP1 (0.44) | ALDH1A1MAPTLMNAL3MBTL1CYP2A6 | |
| SCHEMBL12430519 | 0.73 | CYP2A6 (0.41) | KMT2AALDH1A1MEN1CYP2A6CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4322439-A | ω-[2-(N-Lower alkyl-benzamido)-phenyl]-alkanoic acids, their use, and medicaments containing them | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1982-03-30 | — | — | US | disclosed |
| WO-1979000586-A1 | W-(2-N-LOWER ALKYL-BENZAMIDO)-PHENYL)-ALKANOIC ACIDS,THEIR USE AND PREPARATION,AND MEDICAMENTS CONTAINING THEM | BYK GULDEN LOMBERG CHEM FAB (DE) | 1979-08-23 | — | — | WO | disclosed |