SCHEMBL7410245

SCHEMBL7410245

NCc1ccc2c(c1)CCC2

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.50
RAD52 P43351 1/20 0.50
RXFP1 Q9HBX9 1/20 0.50
CA12 O43570 1/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
CA7 P43166 1/20 0.44
CA14 Q9ULX7 1/20 0.44
TPSAB1 Q15661 1/20 0.43
RXRB P28702 3/20 0.42
ADRA2A P08913 1/20 0.42
ADRA2B P18089 1/20 0.42
ADRA2C P18825 1/20 0.42
STS P08842 1/20 0.41
ALDH1A1 P00352 3/20 0.41
TP53 P04637 2/20 0.41
MAPT P10636 2/20 0.41
KDM4E B2RXH2 1/20 0.41
MEN1 O00255 1/20 0.41
LMNA P02545 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29673223 1.00 KMT2A (0.50) KMT2ARAD52RXFP1CA12CA1
Hydrochloric Acid SCHEMBL5957935 0.98 KMT2A (0.53) KMT2ARAD52RXFP1CA12CA1
SCHEMBL5504129 0.98 KMT2A (0.47) KMT2ARAD52RXFP1CA12CA1
Hydrochloric Acid SCHEMBL5957846 0.95 KMT2A (0.50) KMT2ARAD52RXFP1CA12CA1
SCHEMBL5957796 0.95 KMT2A (0.46) KMT2ARAD52RXFP1CA12CA1
Hydrochloric Acid SCHEMBL6259121 0.93 KMT2A (0.48) KMT2ARAD52RXFP1TPSAB1ADRA2A
SCHEMBL7862464 0.84 TPSAB1 (0.47) KMT2ARAD52RXFP1TPSAB1RXRB
SCHEMBL11276885 0.83 KMT2A (0.41) KMT2ARAD52RXFP1CA12CA1
SCHEMBL5079011 0.83 TAAR1 (0.45) CA12CA1CA2CA7CA14
SCHEMBL30496717 0.83 TAAR1 (0.45) CA12CA1CA2CA7CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119242040-A Heat-resistant high-hardness engineering plastic and preparation method thereof 广州市众拓塑胶模具有限公司 2025-01-03 CN claimed
US-20260042760-A1 COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH CALCITONIN RECEPTOR AND/OR AMYLIN RECEPTOR ACTIVITY ACONCAGUA BIO INC (US) 2026-02-12 US disclosed
US-12486269-B2 Compounds and compositions for treating conditions associated with calcitonin receptor and/or amylin receptor activity ACONCAGUA BIO, INC. (US) 2025-12-02 US disclosed
US-12454525-B2 IL4I1 inhibitors and methods of use MERCK SHARP & DOHME LLC (US) 2025-10-28 US disclosed
US-20250257067-A1 COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH CALCITONIN RECEPTOR AND/OR AMYLIN RECEPTOR ACTIVITY ACONCAGUA BIO, INC. 2025-08-14 US disclosed
CN-119242040-A Heat-resistant high-hardness engineering plastic and preparation method thereof 广州市众拓塑胶模具有限公司 2025-01-03 CN disclosed
CN-119242040-A Heat-resistant high-hardness engineering plastic and preparation method thereof 广州市众拓塑胶模具有限公司 2025-01-03 CN disclosed
US-20230183214-A1 IL4I1 INHIBITORS AND METHODS OF USE MERCK SHARP & DOHME LLC 2023-06-15 US disclosed
US-8524951-B2 Process for production of hydroxyadamantaneamine SHIONOGI & CO., LTD. (JP) 2013-09-03 US disclosed
US-8524951-B2 Process for production of hydroxyadamantaneamine SHIONOGI & CO., LTD. (JP) 2013-09-03 US disclosed
US-8084646-B2 Process for production of hydroxyadamantaneamine SHIONOGI & CO., LTD. (JP) 2011-12-27 US disclosed
US-20110269971-A1 PROCESS FOR PRODUCTION OF HYDROXYADAMANTANEAMINE SHIONOGI & CO., LTD. (JP) 2011-11-03 US disclosed
US-20110269971-A1 PROCESS FOR PRODUCTION OF HYDROXYADAMANTANEAMINE SHIONOGI & CO., LTD. (JP) 2011-11-03 US disclosed
US-20100105923-A1 PROCESS FOR PRODUCTION OF HYDROXYADAMANTANEAMINE SHIONOGI & CO., LTD. (JP) 2010-04-29 US disclosed
US-20100105923-A1 PROCESS FOR PRODUCTION OF HYDROXYADAMANTANEAMINE SHIONOGI & CO., LTD. (JP) 2010-04-29 US disclosed
EP-2088136-A1 PROCESS FOR PRODUCTION OF HYDROXYADAMANTANEAMINE Shionogi Co., Ltd. (JP) 2009-08-12 EP disclosed
EP-0900207-B1 PYRAZINONE THROMBIN INHIBITORS MERCK & CO INC (US) 2001-11-21 EP disclosed
EP-0900207-A1 PYRAZINONE THROMBIN INHIBITORS Merck & Co., Inc. (US) 1999-03-10 EP disclosed
US-5866573-A Pyrazinone thrombin inhibitors MERCK & CO., INC. (US) 1999-02-02 US disclosed
WO-1997040024-A1 PYRAZINONE THROMBIN INHIBITORS MERCK & CO., INC. (US) 1997-10-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12486269-B2 Compounds and compositions for treating conditions associated with calcitonin receptor and/or amylin receptor activity IAPP, GIPR, SCTR KMT2A 4800/4885RAD52 4239/4885RXFP1 170/4885
US-20260042760-A1 COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH CALCITONIN RECEPTOR AND/OR AMYLIN RECEPTOR ACTIVITY NPY1R, CALCRL, SCTR KMT2A 4755/4885RAD52 3741/4885RXFP1 49/4885
US-20250257067-A1 COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH CALCITONIN RECEPTOR AND/OR AMYLIN RECEPTOR ACTIVITY IAPP, GIPR, SCTR KMT2A 4800/4885RAD52 4239/4885RXFP1 170/4885
US-20230183214-A1 IL4I1 INHIBITORS AND METHODS OF USE IL4I1, IL4, IL2 KMT2A 3013/4885RAD52 4448/4885RXFP1 820/4885
US-20100105923-A1 PROCESS FOR PRODUCTION OF HYDROXYADAMANTANEAMINE HAAO, CYP4A11, CYP4F11 KMT2A 2337/4885RAD52 1164/4885RXFP1 3246/4885
US-12454525-B2 IL4I1 inhibitors and methods of use IL4I1, IL4, IL2 KMT2A 3013/4885RAD52 4448/4885RXFP1 820/4885
US-20110269971-A1 PROCESS FOR PRODUCTION OF HYDROXYADAMANTANEAMINE HAAO, CYP4A11, CYP4F11 KMT2A 2337/4885RAD52 1164/4885RXFP1 3246/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.