SCHEMBL11276949

SCHEMBL11276949

CC(C)(O)C1C(=O)N([Si](C)(C)C(C)(C)C)C1Sc1ccccc1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.31
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9815166 0.79 USP2 (0.30) USP2LMNA
SCHEMBL9815156 0.77 POLB (0.35)
SCHEMBL11276956 0.76
SCHEMBL11278410 0.76
SCHEMBL11274041 0.75 ELANE (0.34)
SCHEMBL11277545 0.74
SCHEMBL9815162 0.71 KMT2A (0.35) USP2LMNA
SCHEMBL11279929 0.66
SCHEMBL11171925 0.65
SCHEMBL11171919 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0045198-A2 1,1-Disubstituted carba-2-penems and their production Takeda Chemical Industries, Ltd. (JP) 1982-02-03 EP disclosed