Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 2/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.32 |
| ▸ | LOX | P28300 | 1/20 | 0.32 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 3/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9386008 | 0.82 | RIPK1 (0.33) | LMNAUSP2RIPK1LOXMT-CO2 | |
| SCHEMBL9656949 | 0.77 | — | — | |
| SCHEMBL6073850 | 0.75 | RIPK1 (0.51) | KMT2ARIPK1ALDH1A1BRD4TSHR | |
| SCHEMBL7387880 | 0.75 | TSHR (0.39) | KMT2AMEN1USP2RIPK1ALDH1A1 | |
| SCHEMBL30259456 | 0.75 | TSHR (0.39) | KMT2AMEN1USP2RIPK1ALDH1A1 | |
| SCHEMBL10733391 | 0.73 | — | — | |
| SCHEMBL11276949 | 0.71 | USP2 (0.31) | LMNAUSP2 | |
| SCHEMBL9815166 | 0.70 | USP2 (0.30) | LMNAUSP2 | |
| SCHEMBL10540453 | 0.70 | — | — | |
| SCHEMBL10761187 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0282241-B1 | BETA-LACTAM COMPOUNDS AND PRODUCTION PROCESS THEREOF | Tamura, Yasumitsu (JP) | 1991-08-14 | — | — | EP | disclosed |
| EP-0045198-A2 | 1,1-Disubstituted carba-2-penems and their production | Takeda Chemical Industries, Ltd. (JP) | 1982-02-03 | — | — | EP | disclosed |