Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | HRH2 | P25021 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.46 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | RARB | P10826 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11276971 | 0.97 | RAB9A (0.53) | RAB9AHRH3CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL11302126 | 0.96 | RAB9A (0.52) | RAB9AHRH3CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL11274828 | 0.96 | RAB9A (0.52) | RAB9AHRH3CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL11277730 | 0.96 | RAB9A (0.52) | RAB9AHRH3CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL11279143 | 0.96 | RAB9A (0.52) | RAB9AHRH3CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL11283562 | 0.96 | RAB9A (0.52) | RAB9AHRH3CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL11287135 | 0.96 | RAB9A (0.52) | RAB9AHRH3CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL11285243 | 0.96 | RAB9A (0.52) | RAB9AHRH3CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL24779248 | 0.95 | RAB9A (0.59) | RAB9AHRH3CYP3A4CYP2C9HPGD | |
| SCHEMBL11287806 | 0.94 | RAB9A (0.49) | RAB9AHRH3CYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0022183-B1 | DERIVATIVES OF CYCLOHEXYLBIPHENYL, PROCESS FOR THEIR PREPARATION, DIELECTRICS CONTAINING THEM, AND ELECTRON OPTICAL INDICATING ELEMENTS | MERCK PATENT GmbH (DE) | 1982-06-23 | — | — | EP | disclosed |
| US-4330426-A | Cyclohexylbiphenyls, their preparation and use in dielectrics and electrooptical display elements | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1982-05-18 | — | — | US | disclosed |
| EP-0022183-A2 | Derivatives of cyclohexylbiphenyl, process for their preparation, dielectrics containing them, and electron optical indicating elements | MERCK PATENT GmbH (DE) | 1981-01-14 | — | — | EP | disclosed |