Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SI | P14410 | 1/20 | 0.34 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11267205 | 0.79 | MAPT (0.43) | LMNAKDM4EALDH1A1KMT2AMAPT | |
| SCHEMBL11275966 | 0.78 | TSHR (0.35) | TSHRKDM4EKMT2AMAPT | |
| SCHEMBL11276917 | 0.78 | MAPT (0.50) | LMNAKDM4EALDH1A1KMT2AMAPT | |
| SCHEMBL11259630 | 0.76 | TSHR (0.48) | TSHRLMNAKDM4EALDH1A1KMT2A | |
| SCHEMBL11278421 | 0.75 | KMT2A (0.51) | TSHRKDM4EALDH1A1KMT2AMAPT | |
| SCHEMBL11265815 | 0.75 | KMT2A (0.51) | TSHRKDM4EALDH1A1KMT2AMAPT | |
| SCHEMBL11261558 | 0.75 | KMT2A (0.51) | TSHRKDM4EALDH1A1KMT2AMAPT | |
| SCHEMBL11257799 | 0.75 | KMT2A (0.38) | LMNAKDM4EALDH1A1KMT2AMAPT | |
| SCHEMBL11261713 | 0.72 | CRBN (0.36) | TSHRLMNAKDM4EALDH1A1KMT2A | |
| SCHEMBL22804532 | 0.71 | TSHR (0.48) | TSHRLMNAKDM4EALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4329363-A | Substituted mercapto acid amides and their use | MERCK & CO., INC. (US) | 1982-05-11 | — | — | US | disclosed |
| US-4216160-A | IMMUNOREGULANTS FOR CORRECTING AN INBALANCE OF IMMUNE HOMEOSTASIS | MERCK & CO., INC. (US) | 1980-08-05 | — | — | US | disclosed |
| EP-0001989-A1 | Substituted mercapto acid amides, process for their preparation, pharmaceutical composition containing same and their use | MERCK & CO. INC. (US) | 1979-05-30 | — | — | EP | disclosed |