SCHEMBL11277153

SCHEMBL11277153

FC(F)=C(F)C(F)(F)OC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25435483 1.00 THRB (0.30) THRB
SCHEMBL10600294 0.98
SCHEMBL10969350 0.93
SCHEMBL23912716 0.93
SCHEMBL15821521 0.91
SCHEMBL29366405 0.91
SCHEMBL30578974 0.87
SCHEMBL20324492 0.86
SCHEMBL20324119 0.86
SCHEMBL29453547 0.86

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4349650-A Polyfluoroallyloxy compounds, their preparation and copolymers therefrom E. I. DU PONT DE NEMOURS AND COMPANY (US) 1982-09-14 US disclosed
US-4292449-A Polyfluoroallyloxy compounds, their preparation and copolymers therefrom E. I. DU PONT DE NEMOURS AND COMPANY (US) 1981-09-29 US disclosed
US-4275225-A Polyfluoroallyloxy compounds, their preparation and copolymers therefrom E. I. DU PONT DE NEMOURS AND COMPANY (US) 1981-06-23 US disclosed
US-4273729-A CARBONYL OR SULFONYL FLUORIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1981-06-16 US disclosed
US-4273728-A NITRILES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1981-06-16 US disclosed