SCHEMBL11277221

SCHEMBL11277221

CC(C)(c1ccc(O)cc1)c1ccc(OCCCS(=O)(=O)O)cc1.[NaH]

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 2/20 0.46
CYP3A4 P08684 2/20 0.46
ESR2 Q92731 2/20 0.46
AR P10275 1/20 0.46
HPGD P15428 1/20 0.46
TSHR P16473 1/20 0.46
SLC6A2 P23975 1/20 0.46
SLC6A4 P31645 1/20 0.46
HTR6 P50406 1/20 0.46
ESRRG P62508 1/20 0.46
SLC6A3 Q01959 1/20 0.46
HSD17B10 Q99714 1/20 0.46
S1PR1 P21453 1/20 0.45
KDM4E B2RXH2 8/20 0.45
ALDH1A1 P00352 6/20 0.45
MEN1 O00255 3/20 0.45
KMT2A Q03164 3/20 0.45
HTT P42858 1/20 0.45
LTA4H P09960 3/20 0.44
NR5A1 Q13285 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7601131 0.94 S1PR1 (0.49) CYP3A4S1PR1KDM4EALDH1A1MEN1
SCHEMBL12846186 0.91 ESR1 (0.48) ESR1CYP3A4ESR2ARHPGD
SCHEMBL11480102 0.88 LTA4H (0.50) S1PR1KDM4EALDH1A1MEN1KMT2A
SCHEMBL28335584 0.87 S1PR1 (0.47) ESR1CYP3A4ESR2S1PR1KDM4E
SCHEMBL15480485 0.86 LTA4H (0.52) S1PR1KDM4EALDH1A1MEN1KMT2A
SCHEMBL20486392 0.86 S1PR1 (0.48) ESR1CYP3A4ESR2S1PR1KDM4E
SCHEMBL12870707 0.84 KDM4E (0.42) ESR1CYP3A4ESR2ARHPGD
SCHEMBL6425890 0.83 NR5A1 (0.53) S1PR1KDM4EALDH1A1HTTLTA4H
SCHEMBL11278588 0.81 KDM4E (0.44) CYP3A4S1PR1KDM4EALDH1A1MEN1
SCHEMBL13567687 0.80 LTA4H (0.68) ESR1CYP3A4ESR2ARHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4316838-A SALT OF AN ETHER SULFONATE TEIJIN CHEMICALS LTD. (JP) 1982-02-23 US disclosed
US-4285855-A A POLYCARBONATE BASED ON A DIHYDRIC PHENOL AND A COMPOUND OR RESIN HAVING CARBONATE GROUPS AND ALKALI OR ALKALINE METAL SULFONATE GROUPS TEIJIN CHEMICALS LTD. (JP) 1981-08-25 US disclosed
US-4222910-A SULFURIC ESTER OF AN ALCOHOL OR A METAL SULFONATE COMPOUND TEIJIN CHEMICALS, LTD. (JP) 1980-09-16 US disclosed