Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.79 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | GFER | P55789 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.54 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11277514 | 0.88 | HTT (0.60) | HTTKMT2AGFERMEN1ALDH1A1 | |
| SCHEMBL11278425 | 0.87 | HTT (0.59) | HTTKMT2AGFERMEN1ALDH1A1 | |
| SCHEMBL11286791 | 0.87 | HTT (0.59) | HTTKMT2AGFERMEN1ALDH1A1 | |
| SCHEMBL8742259 | 0.85 | KMT2A (0.79) | HTTKMT2AMEN1CYP2C19ALDH1A1 | |
| SCHEMBL15651281 | 0.82 | HTT (0.79) | HTTKMT2AGFERMEN1CYP2C19 | |
| SCHEMBL17560154 | 0.81 | HTT (0.77) | HTTKMT2AGFERMEN1CYP2C19 | |
| SCHEMBL31499420 | 0.81 | SMN1; SMN2 (0.79) | HTTKMT2AGFERALDH1A1GAA | |
| SCHEMBL31499419 | 0.81 | SMN1; SMN2 (0.79) | HTTKMT2AGFERALDH1A1GAA | |
| SCHEMBL31499418 | 0.81 | SMN1; SMN2 (0.79) | HTTKMT2AGFERALDH1A1GAA | |
| SCHEMBL17560119 | 0.80 | HTT (0.75) | HTTKMT2AGFERMEN1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4327022-A | Heterocyclic alkyl naphthols | STERLING DRUG INC. (US) | 1982-04-27 | — | — | US | disclosed |
| US-4169108-A | 5(OR 6)-[(Substituted-amino)alkyl]-2,3-naphthalenediols | STERLING DRUG INC. (US) | 1979-09-25 | — | — | US | disclosed |