Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 18/20 | 0.64 |
| ▸ | TP53 | P04637 | 3/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | PNMT | P11086 | 1/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.52 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.51 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.51 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.51 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.51 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.51 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.51 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10262038 | 0.84 | SIGMAR1 (0.79) | SIGMAR1TP53CYP1A2MEN1ALDH1A1 | |
| SCHEMBL14614777 | 0.81 | SIGMAR1 (0.64) | SIGMAR1TP53CYP1A2MEN1ALDH1A1 | |
| SCHEMBL2830423 | 0.78 | SIGMAR1 (1.00) | SIGMAR1TP53CYP1A2MEN1ALDH1A1 | |
| SCHEMBL5681292 | 0.78 | SIGMAR1 (1.00) | SIGMAR1TP53CYP1A2MEN1ALDH1A1 | |
| Bromide SCHEMBL1780137 | 0.77 | SIGMAR1 (0.97) | SIGMAR1TP53CYP1A2MEN1ALDH1A1 | |
| Bromide SCHEMBL31601130 | 0.77 | SIGMAR1 (0.97) | SIGMAR1TP53CYP1A2MEN1ALDH1A1 | |
| SCHEMBL14149704 | 0.75 | SIGMAR1 (0.71) | SIGMAR1TP53CYP1A2MEN1ALDH1A1 | |
| SCHEMBL15354609 | 0.74 | SIGMAR1 (0.72) | SIGMAR1TP53CYP1A2MEN1ALDH1A1 | |
| SCHEMBL7319293 | 0.73 | HIF1A (0.61) | TP53CYP1A2ALDH1A1MAPTCYP2D6 | |
| SCHEMBL20457200 | 0.73 | SIGMAR1 (0.72) | SIGMAR1TP53CYP1A2MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4338453-A | Aminoalkyl-1,2,4-triazoles | THE UPJOHN COMPANY (US) | 1982-07-06 | — | — | US | disclosed |