Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.62 |
| ▸ | NQO1 | P15559 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | BLM | P54132 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.59 |
| ▸ | USP2 | O75604 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | TP53 | P04637 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | RECQL | P46063 | 2/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | TOP2A | P11388 | 2/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | MTOR | P42345 | 2/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3148984 | 1.00 | CYP19A1 (0.62) | CYP19A1NQO1SMN1; SMN2MEN1BLM | |
| SCHEMBL3418071 | 1.00 | CYP19A1 (0.62) | CYP19A1NQO1SMN1; SMN2MEN1BLM | |
| SCHEMBL29527683 | 1.00 | CYP19A1 (0.62) | CYP19A1NQO1SMN1; SMN2MEN1BLM | |
| SCHEMBL1202596 | 1.00 | CYP19A1 (0.62) | CYP19A1NQO1SMN1; SMN2MEN1BLM | |
| SCHEMBL30513721 | 1.00 | CYP19A1 (0.62) | CYP19A1NQO1SMN1; SMN2MEN1BLM | |
| SCHEMBL11522777 | 1.00 | CYP19A1 (0.62) | CYP19A1NQO1SMN1; SMN2MEN1BLM | |
| Hydrochloric Acid SCHEMBL11129891 | 0.98 | CYP19A1 (0.60) | CYP19A1NQO1SMN1; SMN2MEN1BLM | |
| SCHEMBL13434543 | 0.95 | CYP19A1 (0.57) | CYP19A1NQO1SMN1; SMN2MEN1BLM | |
| SCHEMBL13434527 | 0.94 | SMN1; SMN2 (0.65) | CYP19A1NQO1SMN1; SMN2MEN1BLM | |
| SCHEMBL12938668 | 0.93 | CYP19A1 (0.55) | CYP19A1NQO1SMN1; SMN2MEN1BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0021622-B1 | 1-(AMINOALKYLAMINO)-5,8-DIHYDROXY-4-SUBSTITUTED-ANTHRAQUINONES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | AMERICAN CYANAMID COMPANY (US) | 1982-10-20 | — | — | EP | claimed |
| US-4275009-A | ANTITUMOR, CHELATION | AMERICAN CYANAMID COMPANY (US) | 1981-06-23 | — | — | US | claimed |
| EP-0021622-A1 | 1-(Aminoalkylamino)-5,8-dihydroxy-4-substituted-anthraquinones, process for their preparation and pharmaceutical compositions containing them | AMERICAN CYANAMID COMPANY (US) | 1981-01-07 | — | — | EP | claimed |
| US-4275009-A | ANTITUMOR, CHELATION | AMERICAN CYANAMID COMPANY (US) | 1981-06-23 | — | — | US | disclosed |
| EP-0021622-A1 | 1-(Aminoalkylamino)-5,8-dihydroxy-4-substituted-anthraquinones, process for their preparation and pharmaceutical compositions containing them | AMERICAN CYANAMID COMPANY (US) | 1981-01-07 | — | — | EP | disclosed |