SCHEMBL3418071

SCHEMBL3418071

CN(C)CCNc1ccc(O)c2c1C(=O)c1c(NCCN(C)C)ccc(O)c1C2=O

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 1/20 0.62
NQO1 P15559 1/20 0.60
SMN1; SMN2 Q16637 3/20 0.59
MEN1 O00255 3/20 0.59
BLM P54132 3/20 0.59
KMT2A Q03164 3/20 0.59
HIF1A Q16665 3/20 0.59
USP2 O75604 2/20 0.59
LMNA P02545 2/20 0.59
TP53 P04637 2/20 0.59
MAPK1 P28482 2/20 0.59
RECQL P46063 2/20 0.59
TDP1 Q9NUW8 2/20 0.59
TOP2A P11388 2/20 0.59
CYP1A2 P05177 2/20 0.59
CYP3A4 P08684 2/20 0.59
CYP2D6 P10635 2/20 0.59
NPC1 O15118 2/20 0.59
MTOR P42345 2/20 0.59
RAB9A P51151 2/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3148984 1.00 CYP19A1 (0.62) CYP19A1NQO1SMN1; SMN2MEN1BLM
SCHEMBL29527683 1.00 CYP19A1 (0.62) CYP19A1NQO1SMN1; SMN2MEN1BLM
SCHEMBL1202596 1.00 CYP19A1 (0.62) CYP19A1NQO1SMN1; SMN2MEN1BLM
SCHEMBL30513721 1.00 CYP19A1 (0.62) CYP19A1NQO1SMN1; SMN2MEN1BLM
SCHEMBL11522777 1.00 CYP19A1 (0.62) CYP19A1NQO1SMN1; SMN2MEN1BLM
SCHEMBL11277491 1.00 CYP19A1 (0.62) CYP19A1NQO1SMN1; SMN2MEN1BLM
Hydrochloric Acid SCHEMBL11129891 0.98 CYP19A1 (0.60) CYP19A1NQO1SMN1; SMN2MEN1BLM
SCHEMBL13434543 0.95 CYP19A1 (0.57) CYP19A1NQO1SMN1; SMN2MEN1BLM
SCHEMBL13434527 0.94 SMN1; SMN2 (0.65) CYP19A1NQO1SMN1; SMN2MEN1BLM
SCHEMBL12938668 0.93 CYP19A1 (0.55) CYP19A1NQO1SMN1; SMN2MEN1BLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9334281-B2 Fluorochromes for organelle tracing and multi-color imaging ENZO LIFE SCIENCES, INC. (US) 2016-05-10 US disclosed
US-9334281-B2 Fluorochromes for organelle tracing and multi-color imaging ENZO LIFE SCIENCES, INC. (US) 2016-05-10 US disclosed
US-9334281-B2 Fluorochromes for organelle tracing and multi-color imaging ENZO LIFE SCIENCES, INC. (US) 2016-05-10 US disclosed
US-8715944-B2 Fluorochromes for organelle tracing and multi-color imaging ENZO LIFE SCIENCES, INC. (US) 2014-05-06 US disclosed
US-8715944-B2 Fluorochromes for organelle tracing and multi-color imaging ENZO LIFE SCIENCES, INC. (US) 2014-05-06 US disclosed
US-8715944-B2 Fluorochromes for organelle tracing and multi-color imaging ENZO LIFE SCIENCES, INC. (US) 2014-05-06 US disclosed
WO-2010028349-A2 FLUOROCHROMES FOR ORGANELLE TRACING AND MULTI-COLOR IMAGING ENZO LIFE SCIENCES, INC. (US) 2010-03-11 WO disclosed
US-20100062429-A1 Fluorochromes for organelle tracing and multi-color imaging ENZO LIFE SCIENCES, INC. 2010-03-11 US disclosed
US-20100062429-A1 Fluorochromes for organelle tracing and multi-color imaging ENZO LIFE SCIENCES, INC. 2010-03-11 US disclosed
US-20100062429-A1 Fluorochromes for organelle tracing and multi-color imaging ENZO LIFE SCIENCES, INC. 2010-03-11 US disclosed
US-20100062460-A1 Novel fluorochromes for organelle tracing and multi-color imaging ENZO LIFE SCIENCES, INC. 2010-03-11 US disclosed
US-20100062460-A1 Novel fluorochromes for organelle tracing and multi-color imaging ENZO LIFE SCIENCES, INC. 2010-03-11 US disclosed
US-20100062460-A1 Novel fluorochromes for organelle tracing and multi-color imaging ENZO LIFE SCIENCES, INC. 2010-03-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100062429-A1 Fluorochromes for organelle tracing and multi-color imaging MFN2, TFEB, NDC1 CYP19A1 4871/4885NQO1 1056/4885SMN1; SMN2 2076/4885
US-20100062460-A1 Novel fluorochromes for organelle tracing and multi-color imaging MFN2, TFEB, NUMA1 CYP19A1 4876/4885NQO1 1089/4885SMN1; SMN2 2265/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.