Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 2/20 | 0.31 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.31 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13822255 | 0.79 | CYP3A4 (0.32) | — | |
| SCHEMBL26893874 | 0.76 | DPP7 (0.34) | DPP4DPP7DPP8 | |
| SCHEMBL9628653 | 0.76 | DPP4 (0.41) | DPP4DPP7DPP8 | |
| SCHEMBL2385435 | 0.75 | — | — | |
| SCHEMBL22455161 | 0.73 | DPP4 (0.36) | DPP4DPP7DPP8 | |
| SCHEMBL7125940 | 0.72 | DPP7 (0.35) | DPP4DPP7DPP8 | |
| SCHEMBL7125939 | 0.72 | DPP7 (0.35) | DPP4DPP7DPP8 | |
| SCHEMBL26893609 | 0.71 | DPP4 (0.34) | DPP4DPP7DPP8 | |
| SCHEMBL5962379 | 0.71 | — | — | |
| SCHEMBL17888242 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0060176-A1 | Substituted trifluoromethylphenyltetrahydropyridines having anorectic activity, their preparation and pharmaceutical compositions containing them | SANOFI S.A. (FR) | 1982-09-15 | — | — | EP | disclosed |