Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.35 |
| ▸ | DPP4 | P27487 | 2/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26893874 | 0.86 | DPP7 (0.34) | DPP7DPP4DPP8 | |
| SCHEMBL22455161 | 0.82 | DPP4 (0.36) | DPP7DPP4DPP8 | |
| SCHEMBL7125939 | 0.81 | DPP7 (0.35) | DPP7DPP4DPP8 | |
| SCHEMBL9628653 | 0.78 | DPP4 (0.41) | DPP7DPP4DPP8 | |
| SCHEMBL23475170 | 0.77 | MEN1 (0.43) | — | |
| SCHEMBL5962379 | 0.72 | — | — | |
| SCHEMBL26893609 | 0.72 | DPP4 (0.34) | DPP7DPP4DPP8 | |
| SCHEMBL11277531 | 0.72 | CTSK (0.31) | DPP7DPP4DPP8 | |
| SCHEMBL3272375 | 0.70 | MAPT (0.35) | — | |
| SCHEMBL6014648 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003047582-A1 | QUINOLINE DERIVATIVES AS ANTITUMOUR AGENTS | ASTRAZENECA AB (SE) | 2003-06-12 | — | — | WO | claimed |
| WO-2003047582-A1 | QUINOLINE DERIVATIVES AS ANTITUMOUR AGENTS | ASTRAZENECA AB (SE) | 2003-06-12 | — | — | WO | disclosed |