Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11285568 | 1.00 | KMT2A (0.54) | KMT2AMEN1POLBATMSMN1; SMN2 | |
| SCHEMBL11270218 | 0.99 | KMT2A (0.55) | KMT2AMEN1POLBATMSMN1; SMN2 | |
| SCHEMBL11272830 | 0.89 | KMT2A (0.58) | KMT2AMEN1POLBATMALDH1A1 | |
| SCHEMBL11278725 | 0.89 | KMT2A (0.58) | KMT2AMEN1POLBATMALDH1A1 | |
| SCHEMBL11270445 | 0.89 | KMT2A (0.58) | KMT2AMEN1POLBATMALDH1A1 | |
| SCHEMBL11282367 | 0.88 | KMT2A (0.59) | KMT2AMEN1POLBATML3MBTL1 | |
| SCHEMBL11284366 | 0.86 | KMT2A (0.53) | KMT2AMEN1POLBATMALDH1A1 | |
| SCHEMBL11282296 | 0.86 | KMT2A (0.56) | KMT2AMEN1POLBATML3MBTL1 | |
| SCHEMBL11285504 | 0.84 | KMT2A (0.52) | KMT2AMEN1POLBATMSMN1; SMN2 | |
| SCHEMBL11272631 | 0.84 | SMN1; SMN2 (0.56) | KMT2AMEN1POLBATMSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4310533-A | INHIBITING PLASMIN AND-OR TRYSIN ACTIVITY | ONO PHARMACEUTICAL CO., LTD. (JP) | 1982-01-12 | — | — | US | disclosed |