Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.60 |
| ▸ | NPC1 | O15118 | 5/20 | 0.50 |
| ▸ | RAB9A | P51151 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.50 |
| ▸ | WNT3A | P56704 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | HSD17B3 | P37058 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | THRA | P10827 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | HTR7 | P34969 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7736066 | 0.94 | GSK3B (0.62) | GSK3BKMT2ANPC1RAB9AMEN1 | |
| SCHEMBL7383618 | 0.94 | GSK3B (0.62) | GSK3BKMT2ANPC1RAB9AMEN1 | |
| SCHEMBL11823872 | 0.88 | GSK3B (0.51) | GSK3BKMT2ANPC1RAB9AMEN1 | |
| SCHEMBL15199328 | 0.88 | GSK3B (0.69) | GSK3BKMT2ANPC1RAB9AMEN1 | |
| SCHEMBL9419411 | 0.87 | KMT2A (0.69) | GSK3BKMT2ANPC1RAB9AMEN1 | |
| SCHEMBL8402203 | 0.85 | KMT2A (0.67) | GSK3BKMT2ANPC1RAB9AMEN1 | |
| SCHEMBL16552778 | 0.83 | KMT2A (0.83) | GSK3BKMT2ANPC1RAB9AMEN1 | |
| SCHEMBL10366079 | 0.82 | NPC1 (0.76) | NPC1RAB9APOLBHSD17B3LMNA | |
| SCHEMBL4839086 | 0.82 | HSD17B3 (0.71) | GSK3BKMT2ANPC1RAB9AMEN1 | |
| SCHEMBL11280840 | 0.82 | GSK3B (0.63) | GSK3BKMT2ANPC1RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4353900-A | HYPOTENSIVE, ANTIARRHYTHMIA, CARDIOTONIC, VASODILATORS | SYNTEX (U.S.A.) INC. (US) | 1982-10-12 | — | — | US | disclosed |