Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.37 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | CSF1R | P07333 | 1/20 | 0.36 |
| ▸ | RET | P07949 | 1/20 | 0.36 |
| ▸ | MET | P08581 | 1/20 | 0.36 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.36 |
| ▸ | PRKACA | P17612 | 1/20 | 0.36 |
| ▸ | LTK | P29376 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11279081 | 0.82 | LMNA (0.47) | TSHRGAAALDH1A1HSD17B10KDM4E | |
| SCHEMBL3938677 | 0.76 | KDM4E (0.45) | GAAALDH1A1HSD17B10KDM4EHPGD | |
| SCHEMBL19503205 | 0.74 | TDP1 (0.51) | TSHRGAAALDH1A1KDM4EHPGD | |
| SCHEMBL10970052 | 0.71 | KDM4E (0.31) | HSD17B10KDM4EHPGD | |
| SCHEMBL22729485 | 0.69 | BRD4 (0.39) | TSHRGAAALDH1A1HSD17B10KDM4E | |
| SCHEMBL14451934 | 0.69 | ATM (0.38) | TSHRGAAALDH1A1HSD17B10KDM4E | |
| SCHEMBL11286998 | 0.69 | KDM4E (0.46) | TSHRGAAALDH1A1HSD17B10KDM4E | |
| SCHEMBL29173842 | 0.67 | KDM4E (0.37) | TSHRGAAALDH1A1HSD17B10KDM4E | |
| SCHEMBL11272207 | 0.67 | KDM4E (0.45) | TSHRGAAALDH1A1HSD17B10KDM4E | |
| SCHEMBL10927533 | 0.66 | BAZ2B (0.50) | GAAALDH1A1HSD17B10KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4363816-A | TREATMENT OF GASTROINTESTINAL DISORDERS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1982-12-14 | — | — | US | disclosed |