Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ANPEP | P15144 | 5/20 | 0.35 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.35 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.32 |
| ▸ | LAP3 | P28838 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9150330 | 0.76 | — | — | |
| SCHEMBL4084344 | 0.72 | TSHR (0.45) | TSHRALDH1A1MAPK1ANPEPERAP1 | |
| SCHEMBL8369038 | 0.69 | TSHR (0.40) | TSHRALDH1A1MAPK1ANPEPERAP1 | |
| SCHEMBL7956491 | 0.65 | ALDH1A1 (0.35) | TSHRALDH1A1MAPK1 | |
| SCHEMBL14569561 | 0.63 | TSHR (0.47) | TSHRALDH1A1MAPK1ANPEPERAP1 | |
| SCHEMBL7057709 | 0.63 | TSHR (0.47) | TSHRALDH1A1MAPK1ANPEPERAP1 | |
| SCHEMBL17452221 | 0.63 | TSHR (0.47) | TSHRALDH1A1MAPK1ANPEPERAP1 | |
| SCHEMBL29531131 | 0.63 | ALDH1A1 (0.33) | TSHRALDH1A1MAPK1 | |
| SCHEMBL21100089 | 0.62 | — | — | |
| SCHEMBL239610 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4354025-A | ANTIOXIDANTS FOR NATURAL AND SYNTHETIC RUBBERS | PETROLITE CORPORATION (US) | 1982-10-12 | — | — | US | disclosed |
| US-4185005-A | Polymer compositions containing as antioxidants substituted hexahydropyrimidines | PETROLITE CORPORATION (US) | 1980-01-22 | — | — | US | disclosed |
| US-4163646-A | STABILIZERS, IMINES | PETROLITE CORPORATION (US) | 1979-08-07 | — | — | US | disclosed |
| US-4129597-A | Amino compounds and use thereof as antioxidants | PETROLITE CORPORATION (US) | 1978-12-12 | — | — | US | disclosed |