Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | MAOA | P21397 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.58 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.58 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.58 |
| ▸ | BCHE | P06276 | 1/20 | 0.58 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.56 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.56 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10609652 | 0.82 | LMNA (0.75) | MAOBGAAMAPTMAOARAB9A | |
| SCHEMBL339813 | 0.82 | LMNA (0.82) | MAOBGAAMAPTMAOARAB9A | |
| SCHEMBL1691467 | 0.81 | MAOB (0.61) | MAOBGAAMAPTMAOARAB9A | |
| SCHEMBL324079 | 0.79 | SLC6A2 (0.50) | MAOBMAOASMN1; SMN2LMNACYP1A2 | |
| SCHEMBL5390078 | 0.79 | PPARG (0.57) | MAOBGAAMAPTMAOARAB9A | |
| SCHEMBL21483725 | 0.79 | PTGS1 (0.59) | MAOBGAAMAPTMAOARAB9A | |
| SCHEMBL11579580 | 0.79 | SLC6A2 (0.66) | MAOBGAAMAPTMAOARAB9A | |
| SCHEMBL703 | 0.79 | LMNA (0.64) | MAOBGAAMAPTMAOARAB9A | |
| SCHEMBL10599543 | 0.78 | LMNA (0.69) | MAOBGAAMAPTMAOARAB9A | |
| SCHEMBL11856925 | 0.78 | LMNA (0.69) | MAOBGAAMAPTMAOARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0051196-A1 | 4-Benzyloxy-alpha-trichloromethylbenzyl amines, process for their preparation, pesticidal compositions containing them, their preparation and use | BAYER AG (DE) | 1982-05-12 | — | — | EP | disclosed |