SCHEMBL11277910

SCHEMBL11277910

S=P(S)(Cl)Oc1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.46
TDP1 Q9NUW8 1/20 0.46
SRC P12931 1/20 0.43
HSD17B10 Q99714 1/20 0.38
LTA4H P09960 1/20 0.38
TSHR P16473 1/20 0.38
KDM4E B2RXH2 1/20 0.38
CA4 P22748 2/20 0.35
HTT P42858 2/20 0.34
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
CA12 O43570 1/20 0.34
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
CA5A P35218 1/20 0.34
CA7 P43166 1/20 0.34
CA9 Q16790 1/20 0.34
CA5B Q9Y2D0 1/20 0.34
TP53 P04637 1/20 0.33
GAA P10253 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3077418 0.80 SRC (0.46) L3MBTL1TDP1SRCHSD17B10LTA4H
SCHEMBL789902 0.80 SRC (0.46) L3MBTL1TDP1SRCHSD17B10LTA4H
SCHEMBL1158054 0.80 SRC (0.46) L3MBTL1TDP1SRCHSD17B10LTA4H
SCHEMBL5850888 0.80 SRC (0.46) L3MBTL1TDP1SRCHSD17B10LTA4H
SCHEMBL40604 0.79 SRC (0.50) L3MBTL1TDP1SRCHSD17B10LTA4H
Ammonia Solution, Strong SCHEMBL7759745 0.78 SRC (0.44) L3MBTL1TDP1SRCHSD17B10LTA4H
SCHEMBL11245340 0.77 CYP1A2 (0.46) HTTKMT2ATP53GAA
SCHEMBL5850893 0.76 SRC (0.43) L3MBTL1TDP1SRCHSD17B10LTA4H
SCHEMBL3066702 0.76 SRC (0.54) L3MBTL1TDP1SRCHSD17B10LTA4H
SCHEMBL10614739 0.76 SRC (0.43) L3MBTL1TDP1SRCHSD17B10LTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4317887-A NUCLEOPHILIC-MODIFIED POLYACRYLAMIDE, POLYSTYRENE, AND DIVINYLBENZENE-STYRENE COPOLYMER; ION EXCHANGE RESINS; FIREPROOFING YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 1982-03-02 US disclosed