SCHEMBL11245340

SCHEMBL11245340

S=P(S)(Cl)Oc1cccc(Cl)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.46
CYP2C9 P11712 2/20 0.46
CYP2C19 P33261 2/20 0.46
CYP2D6 P10635 1/20 0.46
HTT P42858 2/20 0.39
WDR5 P61964 1/20 0.39
LMNA P02545 1/20 0.38
MAPK1 P28482 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
SLC6A4 P31645 2/20 0.36
DRD2 P14416 1/20 0.36
DRD4 P21917 1/20 0.36
SLC6A2 P23975 1/20 0.36
SLC6A3 Q01959 1/20 0.36
KCNH2 Q12809 1/20 0.35
RHEB Q15382 1/20 0.35
OGG1 O15527 1/20 0.35
KMT2A Q03164 1/20 0.35
BCHE P06276 1/20 0.35
TP53 P04637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11277910 0.77 L3MBTL1 (0.46) HTTKMT2ATP53GAA
SCHEMBL11099147 0.76 CYP1A2 (0.57) CYP1A2CYP2C9CYP2C19CYP2D6HTT
SCHEMBL8849551 0.76 CYP1A2 (0.57) CYP1A2CYP2C9CYP2C19CYP2D6HTT
SCHEMBL31561763 0.76 CYP1A2 (0.57) CYP1A2CYP2C9CYP2C19CYP2D6HTT
SCHEMBL9259535 0.74 CYP1A2 (0.59) CYP1A2CYP2C9CYP2C19CYP2D6HTT
SCHEMBL11053438 0.73 CYP1A2 (0.54) CYP1A2CYP2C9CYP2C19CYP2D6HTT
SCHEMBL7602618 0.71 SRC (0.58) CYP1A2CYP2C9CYP2C19CYP2D6HTT
SCHEMBL29093880 0.71 CYP1A2 (0.56) CYP1A2CYP2C9CYP2C19CYP2D6HTT
SCHEMBL11771178 0.70 WDR5 (0.44) CYP1A2CYP2C9CYP2C19CYP2D6HTT
SCHEMBL8124927 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4322414-A MITICIDES; APHIDICIDES; LARVICIDES VELSICOL CHEMICAL CORPORATION (US) 1982-03-30 US disclosed