SCHEMBL11277916

SCHEMBL11277916

O=C(O)C(F)(F)C(F)(OC(F)(F)C(F)=C(F)F)C(F)(F)C(=O)O

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.33
ACLY P53396 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11273986 0.84
SCHEMBL30474859 0.83 THRB (0.33) THRBACLY
SCHEMBL11277540 0.78
SCHEMBL11283106 0.78 THRB (0.43) THRB
SCHEMBL11277613 0.76 THRB (0.47) THRB
SCHEMBL9751874 0.76
SCHEMBL11366824 0.74 MEN1 (0.35) THRB
SCHEMBL302963 0.72
Ammonia Solution, Strong SCHEMBL27438287 0.72
Ammonia Solution, Strong SCHEMBL27436513 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4349650-A Polyfluoroallyloxy compounds, their preparation and copolymers therefrom E. I. DU PONT DE NEMOURS AND COMPANY (US) 1982-09-14 US disclosed
US-4304927-A Carboxylic acids, esters and salts of polyfluoroacetone E. I. DUPONT DE NEMOURS AND COMPANY (US) 1981-12-08 US disclosed
US-4292449-A Polyfluoroallyloxy compounds, their preparation and copolymers therefrom E. I. DU PONT DE NEMOURS AND COMPANY (US) 1981-09-29 US disclosed
US-4275225-A Polyfluoroallyloxy compounds, their preparation and copolymers therefrom E. I. DU PONT DE NEMOURS AND COMPANY (US) 1981-06-23 US disclosed
US-4273729-A CARBONYL OR SULFONYL FLUORIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1981-06-16 US disclosed
US-4273728-A NITRILES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1981-06-16 US disclosed