Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11276369 | 0.94 | TSHR (0.41) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL11293409 | 0.92 | TSHR (0.36) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL11291860 | 0.85 | TSHR (0.40) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL9421229 | 0.85 | TSHR (0.40) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL7609199 | 0.84 | TSHR (0.49) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL9358119 | 0.78 | TSHR (0.45) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL9862364 | 0.77 | TSHR (0.44) | TSHRTHRB | |
| SCHEMBL10895402 | 0.77 | TSHR (0.44) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL9354412 | 0.76 | TSHR (0.49) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL10537263 | 0.74 | TSHR (0.47) | TSHRPOLBAPEX1HTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0067909-A1 | Oxygen permeable hard and semi-hard contact lens compositions, processes for their preparation, contact lenses and their manufacture from such compositions | SYNTEX (U.S.A.) INC. (US) | 1982-12-29 | — | — | EP | claimed |
| US-4242483-A | FROM AN UNSATURATED SILICON CONTAINING MONOMER AND AN ACRYLIC OR METHACRYLIC ESTER OR ITACONATE ESTER | SYNTEX OPHTHALMICS, INC., | 1980-12-30 | — | — | US | claimed |
| EP-0067909-A1 | Oxygen permeable hard and semi-hard contact lens compositions, processes for their preparation, contact lenses and their manufacture from such compositions | SYNTEX (U.S.A.) INC. (US) | 1982-12-29 | — | — | EP | disclosed |
| US-4242483-A | FROM AN UNSATURATED SILICON CONTAINING MONOMER AND AN ACRYLIC OR METHACRYLIC ESTER OR ITACONATE ESTER | SYNTEX OPHTHALMICS, INC., | 1980-12-30 | — | — | US | disclosed |