Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11276369 | 0.83 | TSHR (0.41) | TSHRALDH1A1THRB | |
| SCHEMBL11278056 | 0.77 | TSHR (0.38) | TSHRTHRB | |
| SCHEMBL374776 | 0.75 | TSHR (0.57) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL712918 | 0.75 | TSHR (0.57) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL331043 | 0.75 | TSHR (0.57) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL344379 | 0.75 | TSHR (0.57) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL3597832 | 0.74 | TSHR (0.49) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL11293409 | 0.74 | TSHR (0.36) | TSHRTHRB | |
| SCHEMBL395328 | 0.73 | TSHR (0.55) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL395892 | 0.73 | TSHR (0.55) | TSHRHPGDALDH1A1CYP3A4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5032658-A | Hardness, unsaturated ester | POLYMER TECHNOLOGY CORPORATION (US) | 1991-07-16 | — | — | US | disclosed |