SCHEMBL11278393

SCHEMBL11278393

CC(C)CNC(=O)N(C)C(=O)Nc1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MTOR P42345 2/20 0.53
KMT2A Q03164 4/20 0.49
NPC1 O15118 2/20 0.49
RAB9A P51151 2/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
LMNA P02545 4/20 0.47
ALDH1A1 P00352 3/20 0.47
MAPT P10636 2/20 0.47
ALOX12 P18054 1/20 0.47
MEN1 O00255 2/20 0.46
HPGD P15428 2/20 0.45
NPSR1 Q6W5P4 2/20 0.45
GAA P10253 1/20 0.45
HSD17B10 Q99714 1/20 0.45
NPY5R Q15761 1/20 0.45
ATM Q13315 1/20 0.43
TP53 P04637 1/20 0.43
POLB P06746 1/20 0.43
THRB P10828 1/20 0.43
HDAC1 Q13547 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11266003 0.84 MTOR (0.46) MTORKMT2AALDH1A1MEN1HPGD
SCHEMBL11265941 0.82 MEN1 (0.54) MTORKMT2ANPC1RAB9ASMN1; SMN2
SCHEMBL11270939 0.81 ABAT (0.56) MTORKMT2ASMN1; SMN2ALDH1A1MEN1
SCHEMBL11264746 0.79 KMT2A (0.54) MTORKMT2ANPC1RAB9ASMN1; SMN2
SCHEMBL11258765 0.79 KMT2A (0.47) MTORKMT2ANPC1RAB9ASMN1; SMN2
SCHEMBL11264532 0.79 MTOR (0.57) MTORKMT2ASMN1; SMN2LMNAALDH1A1
SCHEMBL10596294 0.78 LMNA (0.61) KMT2ANPC1RAB9ASMN1; SMN2LMNA
SCHEMBL11263216 0.78 MEN1 (0.46) MTORKMT2ANPC1RAB9ASMN1; SMN2
SCHEMBL11262889 0.78 MEN1 (0.46) MTORKMT2ALMNAALDH1A1MEN1
SCHEMBL11266248 0.77 MEN1 (0.45) MTORKMT2ARAB9ASMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4350700-A ANALGESIC, ANTIINFLAMMATORY, ANTIPYRETIC TAIHO PHARMACEUTICAL COMPANY, LIMITED (JP) 1982-09-21 US disclosed
US-4287207-A USED AS AN ANALGESIC, ANTIPYRETIC OR ANTIINFLAMMATORY AGENT TAIHO PHARMACEUTICAL COMPANY, LIMITED (JP) 1981-09-01 US disclosed