Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 3/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 2/20 | 0.35 |
| ▸ | PPARA | Q07869 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13980918 | 1.00 | MAPT (0.45) | MAPTABCC4ALDH1A1TSHRLMNA | |
| SCHEMBL8738053 | 0.85 | TSHR (0.48) | MAPTABCC4ALDH1A1TSHRLMNA | |
| SCHEMBL2691938 | 0.85 | TSHR (0.48) | MAPTABCC4ALDH1A1TSHRLMNA | |
| SCHEMBL18623650 | 0.85 | TSHR (0.48) | MAPTABCC4ALDH1A1TSHRLMNA | |
| SCHEMBL22492168 | 0.85 | TSHR (0.48) | MAPTABCC4ALDH1A1TSHRLMNA | |
| SCHEMBL23631357 | 0.85 | TSHR (0.48) | MAPTABCC4ALDH1A1TSHRLMNA | |
| SCHEMBL18691950 | 0.84 | MAPT (0.64) | MAPTABCC4ALDH1A1TSHRLMNA | |
| SCHEMBL28244058 | 0.84 | MAPT (0.64) | MAPTABCC4ALDH1A1TSHRLMNA | |
| SCHEMBL11746010 | 0.84 | MAPT (0.64) | MAPTABCC4ALDH1A1TSHRLMNA | |
| SCHEMBL6557587 | 0.83 | ALDH1A1 (0.50) | MAPTABCC4ALDH1A1TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0012390-B1 | PROCESS FOR THE PREPARATION OF MUSCONE; THE INTERMEDIATE PYRANIC COMPOUNDS | FIRMENICH SA (CH) | 1982-11-24 | — | — | EP | disclosed |
| US-4341897-A | Pyranic derivatives for use in the preparation of muscone | FIRMENICH SA (CH) | 1982-07-27 | — | — | US | disclosed |
| US-4277625-A | Process for the preparation of muscone | FIRMENICH SA (CH) | 1981-07-07 | — | — | US | disclosed |
| EP-0012390-A2 | Process for the preparation of muscone; the intermediate pyranic compounds | FIRMENICH SA (CH) | 1980-06-25 | — | — | EP | disclosed |