Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.67 |
| ▸ | HTT | P42858 | 4/20 | 0.61 |
| ▸ | MAPT | P10636 | 5/20 | 0.60 |
| ▸ | LMNA | P02545 | 5/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.50 |
| ▸ | CTSV | O60911 | 1/20 | 0.50 |
| ▸ | CTSL | P07711 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11283392 | 0.86 | ALDH1A1 (0.60) | ALDH1A1SMN1; SMN2HTTMAPTLMNA | |
| SCHEMBL11284594 | 0.83 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2HTTMAPTLMNA | |
| SCHEMBL11100421 | 0.82 | ALDH1A1 (0.73) | ALDH1A1SMN1; SMN2HTTMAPTLMNA | |
| SCHEMBL10502203 | 0.81 | ALDH1A1 (0.97) | ALDH1A1SMN1; SMN2HTTMAPTLMNA | |
| SCHEMBL1972566 | 0.81 | ALDH1A1 (0.75) | ALDH1A1SMN1; SMN2HTTMAPTLMNA | |
| SCHEMBL6255487 | 0.80 | ALDH1A1 (1.00) | ALDH1A1SMN1; SMN2HTTMAPTLMNA | |
| SCHEMBL3040101 | 0.80 | ALDH1A1 (1.00) | ALDH1A1SMN1; SMN2HTTMAPTLMNA | |
| SCHEMBL29805486 | 0.80 | ALDH1A1 (1.00) | ALDH1A1SMN1; SMN2HTTMAPTLMNA | |
| SCHEMBL701594 | 0.78 | MAPT (0.57) | ALDH1A1SMN1; SMN2HTTMAPTLMNA | |
| SCHEMBL29978606 | 0.78 | MAPT (0.57) | ALDH1A1SMN1; SMN2HTTMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0056144-A1 | Carboxylic acid derivatives, their preparation and use as pharmaceuticals | Dr. Karl Thomae GmbH (DE) | 1982-07-21 | — | — | EP | disclosed |