Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Cephaloglycin. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 1.00 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.73 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.71 |
| ▸ | MAPT | P10636 | 7/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.70 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.70 |
| ▸ | HPGD | P15428 | 4/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.70 |
| ▸ | SLC15A2 | Q16348 | 3/20 | 0.70 |
| ▸ | BLM | P54132 | 1/20 | 0.70 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.70 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.70 |
| ▸ | HTR2B | P41595 | 1/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.67 |
| ▸ | MEN1 | O00255 | 3/20 | 0.67 |
| ▸ | NR1I2 | O75469 | 3/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.67 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cephaloglycin SCHEMBL11419396 | 1.00 | PTGS1 (1.00) | PTGS1L3MBTL1TDP1MAPTALDH1A1 | |
| Cephaloglycin SCHEMBL6154818 | 1.00 | PTGS1 (1.00) | PTGS1L3MBTL1TDP1MAPTALDH1A1 | |
| Cephaloglycin SCHEMBL11742799 | 1.00 | PTGS1 (1.00) | PTGS1L3MBTL1TDP1MAPTALDH1A1 | |
| Cephaloglycin SCHEMBL16072815 | 1.00 | PTGS1 (1.00) | PTGS1L3MBTL1TDP1MAPTALDH1A1 | |
| Cephaloglycin SCHEMBL11635204 | 1.00 | PTGS1 (1.00) | PTGS1L3MBTL1TDP1MAPTALDH1A1 | |
| Cephaloglycin SCHEMBL10703211 | 1.00 | PTGS1 (1.00) | PTGS1L3MBTL1TDP1MAPTALDH1A1 | |
| Cephaloglycin SCHEMBL11222714 | 1.00 | PTGS1 (1.00) | PTGS1L3MBTL1TDP1MAPTALDH1A1 | |
| Cephaloglycin SCHEMBL11635199 | 1.00 | PTGS1 (1.00) | PTGS1L3MBTL1TDP1MAPTALDH1A1 | |
| Cephaloglycin SCHEMBL2947 | 1.00 | PTGS1 (1.00) | PTGS1L3MBTL1TDP1MAPTALDH1A1 | |
| Cephaloglycin SCHEMBL8480395 | 1.00 | PTGS1 (1.00) | PTGS1L3MBTL1TDP1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4341776-A | BACTERICIDES | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1982-07-27 | — | — | US | disclosed |
| US-4328224-A | ANTIBIOTICS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1982-05-04 | — | — | US | disclosed |
| US-4301161-A | BACTERICIDES | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1981-11-17 | — | — | US | disclosed |
| US-4298605-A | ANTIBIOTICS, BACTERICIDES | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1981-11-03 | — | — | US | disclosed |
| US-4294827-A | CEPHALOSPORINS OR PENICILLINS | BAYER AKTIENGESELLSCHAFT (DE) | 1981-10-13 | — | — | US | disclosed |
| US-4258184-A | ANTIBIOTICS | MEIJI SEIKA KAISHA LTD. (JP) | 1981-03-24 | — | — | US | disclosed |
| US-4251524-A | ANIMAL GROWTH REGULATORS | BAYER AKTIENGESELLSCHAFT (DE) | 1981-02-17 | — | — | US | disclosed |
| US-4224442-A | 7-Ureido acetamido substituted cephalosporin antibiotics | ELI LILLY AND COMPANY (US) | 1980-09-23 | — | — | US | disclosed |
| US-4223037-A | ANIMAL GROWTH PROMOTER, BACTERICIDES, PENICILLINS | BAYER AKTIENGESELLSCHAFT (DE) | 1980-09-16 | — | — | US | disclosed |
| US-4208412-A | β-Lactam antibiotics | BAYER AKTIENGESELLSCHAFT (DE) | 1980-06-17 | — | — | US | disclosed |
| US-4071683-A | ANTIBIOTICS | BAYER AKTIENGESELLSCHAFT (DT) | 1978-01-31 | — | — | US | disclosed |
| US-4059432-A | A 2-SULFONYLOXYETHYL-PHOSPHONIC OR -THIONOPHOSPHONIC ACID DERIVATIVE | MITSUBISHI PETROCHEMICAL CO., LTD. (JA) | 1977-11-22 | — | — | US | disclosed |
| US-4059431-A | A 2-SULFONYLOXYETHYL-PHOSPHONIC OR -THIONOPHOSPHONIC ACID DERIVATIVE | MITSUBISHI PETROCHEMICAL CO., LTD. (JA) | 1977-11-22 | — | — | US | disclosed |
| US-4039673-A | BACTERICIDES | BAYER AKTIENGESELLSCHAFT (DT) | 1977-08-02 | — | — | US | disclosed |
| US-4029806-A | Nitro-β-lactam antibiotics and processes for their preparation and use | BAYER AKTIENGESELLSCHAFT (DT) | 1977-06-14 | — | — | US | disclosed |
| US-4029651-A | ESTERIFICATION | ELI LILLY AND COMPANY (US) | 1977-06-14 | — | — | US | disclosed |
| US-4025622-A | ANTIBACTERIAL | Ogura, Haruo (JA) | 1977-05-24 | — | — | US | disclosed |
| US-4012518-A | PENICILLIN DERIVATIVES AS GROWTH AND FEED UTILIZATION PROMOTERS IN ANIMALS | BAYER AKTIENGESELLSCHAFT (DT) | 1977-03-15 | — | — | US | disclosed |
| US-3988326-A | Process for N-acylation of 7 amino cephem compounds | MEIJI SEIKA KAISHA, LTD. (JA) | 1976-10-26 | — | — | US | disclosed |
| US-3966709-A | Penicillins and cephalosporins and their production | BAYER AKTIENGESELLSCHAFT (DT) | 1976-06-29 | — | — | US | disclosed |