Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 12/20 | 0.74 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.56 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.56 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.56 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.56 |
| ▸ | HTR2A | P28223 | 5/20 | 0.51 |
| ▸ | HTR2C | P28335 | 4/20 | 0.51 |
| ▸ | MAPKAPK2 | P49137 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL945550 | 0.85 | S1PR1 (1.00) | S1PR1S1PR2S1PR4S1PR3S1PR5 | |
| SCHEMBL11317821 | 0.85 | KMT2A (0.71) | S1PR1S1PR2S1PR4S1PR3S1PR5 | |
| SCHEMBL946725 | 0.84 | S1PR1 (0.78) | S1PR1S1PR2S1PR4S1PR3S1PR5 | |
| SCHEMBL947705 | 0.84 | S1PR1 (0.78) | S1PR1S1PR2S1PR4S1PR3S1PR5 | |
| SCHEMBL945023 | 0.84 | S1PR1 (0.78) | S1PR1S1PR2S1PR4S1PR3S1PR5 | |
| SCHEMBL28961219 | 0.82 | HTR2A (0.70) | S1PR1HTR2AHTR2CMAPKAPK2 | |
| SCHEMBL11277982 | 0.82 | S1PR1 (0.60) | S1PR1HTR2AHTR2CMAPKAPK2KMT2A | |
| SCHEMBL30397112 | 0.82 | HTR2A (0.70) | S1PR1HTR2AHTR2CMAPKAPK2 | |
| SCHEMBL945492 | 0.80 | S1PR1 (0.76) | S1PR1S1PR2S1PR4S1PR3S1PR5 | |
| SCHEMBL945493 | 0.80 | S1PR1 (0.76) | S1PR1S1PR2S1PR4S1PR3S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4336256-A | TREATMENT OF ANOXIA, DEPRESSION AND IN PSYCHOTROPIC THERAPY | SYNTHELABO (FR) | 1982-06-22 | — | — | US | disclosed |