Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 8/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | HTR2A | P28223 | 5/20 | 0.57 |
| ▸ | HTR2C | P28335 | 5/20 | 0.57 |
| ▸ | HTR2B | P41595 | 2/20 | 0.56 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.55 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11314589 | 0.86 | KMT2A (0.77) | S1PR1KMT2AHTR2AHTR2CHTR2B | |
| SCHEMBL30397112 | 0.85 | HTR2A (0.70) | S1PR1HTR2AHTR2CHTR2BSIRT1 | |
| SCHEMBL28961219 | 0.85 | HTR2A (0.70) | S1PR1HTR2AHTR2CHTR2BSIRT1 | |
| SCHEMBL6237686 | 0.85 | KMT2A (0.76) | S1PR1KMT2AHTR2AHTR2CHTR2B | |
| SCHEMBL5538606 | 0.85 | HTR2A (0.62) | HTR2AHTR2CHTR2B | |
| Hydrochloric Acid SCHEMBL6350788 | 0.84 | KMT2A (0.77) | S1PR1KMT2AHTR2AHTR2CHTR2B | |
| SCHEMBL11278643 | 0.82 | S1PR1 (0.74) | S1PR1KMT2AHTR2AHTR2CMAPKAPK2 | |
| SCHEMBL3246180 | 0.82 | GRIN2B (0.67) | S1PR1HTR2AHTR2CMAPKAPK2 | |
| SCHEMBL6238971 | 0.81 | MAPKAPK2 (0.74) | HTR2AHTR2CHTR2BSIRT1MAPKAPK2 | |
| SCHEMBL25147653 | 0.80 | SIRT1 (0.60) | S1PR1SIRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4336256-A | TREATMENT OF ANOXIA, DEPRESSION AND IN PSYCHOTROPIC THERAPY | SYNTHELABO (FR) | 1982-06-22 | — | — | US | disclosed |