Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.69 |
| ▸ | PPARD | Q03181 | 2/20 | 0.69 |
| ▸ | PPARA | Q07869 | 2/20 | 0.69 |
| ▸ | LMNA | P02545 | 2/20 | 0.69 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.69 |
| ▸ | MAPT | P10636 | 1/20 | 0.69 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.69 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.69 |
| ▸ | BLM | P54132 | 1/20 | 0.69 |
| ▸ | CYSLTR2 | Q9NS75 | 16/20 | 0.67 |
| ▸ | CYSLTR1 | Q9Y271 | 16/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | GLA | P06280 | 1/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.63 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.63 |
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.63 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6247680 | 0.93 | PPARG (0.75) | PPARGPPARDPPARALMNAGRM2 | |
| Thiocyanic Acid SCHEMBL10687792 | 0.92 | PPARG (0.61) | PPARGPPARDPPARALMNAGRM2 | |
| SCHEMBL10702435 | 0.91 | GRM2 (0.73) | PPARGPPARDPPARALMNAGRM2 | |
| SCHEMBL4915595 | 0.90 | PPARG (0.65) | PPARGPPARDPPARALMNAGRM2 | |
| SCHEMBL11050054 | 0.90 | PPARG (0.65) | PPARGPPARDPPARALMNAGRM2 | |
| SCHEMBL10522351 | 0.90 | CYSLTR2 (0.72) | PPARGPPARDPPARALMNAGRM2 | |
| SCHEMBL6932399 | 0.90 | PPARG (0.68) | PPARGPPARDPPARALMNAGRM2 | |
| SCHEMBL10505686 | 0.90 | PPARG (0.68) | PPARGPPARDPPARALMNAGRM2 | |
| SCHEMBL6934984 | 0.90 | PPARG (0.65) | PPARGPPARDPPARALMNAGRM2 | |
| Bicarbonate SCHEMBL10790750 | 0.90 | PPARG (0.76) | PPARGPPARDPPARALMNAGRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0054398-A1 | Pharmacologically active benzopyrano-(2,3-d)-v-triazoles | BEECHAM GROUP PLC (GB) | 1982-06-23 | — | — | EP | disclosed |