Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.68 |
| ▸ | PPARD | Q03181 | 2/20 | 0.68 |
| ▸ | PPARA | Q07869 | 2/20 | 0.68 |
| ▸ | LMNA | P02545 | 2/20 | 0.68 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.68 |
| ▸ | MAPT | P10636 | 1/20 | 0.68 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.68 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.68 |
| ▸ | BLM | P54132 | 1/20 | 0.68 |
| ▸ | CYSLTR2 | Q9NS75 | 16/20 | 0.67 |
| ▸ | CYSLTR1 | Q9Y271 | 16/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | GLA | P06280 | 1/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.63 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.63 |
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.63 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6934984 | 0.94 | PPARG (0.65) | PPARGPPARDPPARALMNAGRM2 | |
| SCHEMBL6247680 | 0.92 | PPARG (0.75) | PPARGPPARDPPARALMNAGRM2 | |
| SCHEMBL10702435 | 0.90 | GRM2 (0.73) | PPARGPPARDPPARALMNAGRM2 | |
| SCHEMBL11279092 | 0.90 | PPARG (0.69) | PPARGPPARDPPARALMNAGRM2 | |
| SCHEMBL10522351 | 0.89 | CYSLTR2 (0.72) | PPARGPPARDPPARALMNAGRM2 | |
| SCHEMBL10505686 | 0.89 | PPARG (0.68) | PPARGPPARDPPARALMNAGRM2 | |
| Bicarbonate SCHEMBL10790750 | 0.89 | PPARG (0.76) | PPARGPPARDPPARALMNAGRM2 | |
| SCHEMBL10815053 | 0.88 | PPARG (0.67) | PPARGPPARDPPARALMNAGRM2 | |
| SCHEMBL11046915 | 0.88 | PPARG (0.74) | PPARGPPARDPPARALMNAGRM2 | |
| SCHEMBL4343526 | 0.88 | PPARG (0.67) | PPARGPPARDPPARALMNAGRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4202155-A | — | — | None | — | — | JP | disclosed |
| JP-4202155-A | — | — | None | — | — | JP | disclosed |
| EP-1086079-B1 | DERIVATIVES OF HYDROXYPHENYLSULFANYLBENZOIC AND HYDROXYPHENYLSULFANYLARYLACETIC ACIDS | LECIVA A S (CZ) | 2003-05-07 | — | — | EP | disclosed |
| US-6303612-B1 | USED AS ANTIINFLAMMATORY AND/OR ANTIASTHMATIC AGENTS | LECIVA, A.S. (CZ) | 2001-10-16 | — | — | US | disclosed |
| EP-1086079-A1 | DERIVATIVES OF HYDROXYPHENYLSULFANYLBENZOIC AND HYDROXYPHENYLSULFANYLARYLACETIC ACIDS | Leciva, A.S. (CZ) | 2001-03-28 | — | — | EP | disclosed |
| WO-1999067208-A1 | DERIVATIVES OF HYDROXYPHENYLSULFANYLBENZOIC AND HYDROXYPHENYLSULFANYLARYLACETIC ACIDS | LECIVA, A.S. (CZ) | 1999-12-29 | — | — | WO | disclosed |
| US-5559134-A | Leukotriene-B4 antagonists, process for their production and their use as pharmaceutical agents | SCHERING AKTIENGESELLSCHAFT (DE) | 1996-09-24 | — | — | US | disclosed |
| EP-0181779-B1 | Heterocyclic compounds, their production, and medicaments containing them | YAMANOUCHI PHARMA CO LTD (JP) | 1994-03-16 | — | — | EP | disclosed |
| US-5258395-A | Slow reacting substance of anaphylaxis antagonists | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1993-11-02 | — | — | US | disclosed |
| US-5177215-A | Heterocyclic compounds and pharmaceutical use thereof | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1993-01-05 | — | — | US | disclosed |
| US-4889871-A | ANTIINFLAMMATORY AGENTS; SELECTIVE LEUKOTRIENE ANTAGONISTS | G. D. SEARLE & CO. (US) | 1989-12-26 | — | — | US | disclosed |
| US-4855310-A | Thiadiazole compounds as antagonists of SRS-A | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1989-08-08 | — | — | US | disclosed |
| EP-0292977-A1 | Alkoxy-substituted dihydrobenzopyran-2-carboxylate derivatives | G.D. Searle & Co. (US) | 1988-11-30 | — | — | EP | disclosed |
| US-4714774-A | ANTIASTHMATIC OR ANTIINFLAMMATORY AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1987-12-22 | — | — | US | disclosed |
| EP-0186440-A2 | Method for producing benzoic acid derivatives | Takeda Chemical Industries, Ltd. (JP) | 1986-07-02 | — | — | EP | disclosed |
| EP-0181779-A1 | Heterocyclic compounds, their production, and medicaments containing them | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1986-05-21 | — | — | EP | disclosed |
| EP-0181125-A2 | Benzoic acid derivatives and their production | Takeda Chemical Industries, Ltd. (JP) | 1986-05-14 | — | — | EP | disclosed |
| EP-0180416-A2 | Benzoic acid analogues and their production | Takeda Chemical Industries, Ltd. (JP) | 1986-05-07 | — | — | EP | disclosed |
| EP-0028063-B1 | PHENOL DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLAXO GROUP LIMITED (GB) | 1984-06-13 | — | — | EP | disclosed |
| EP-0028063-A1 | Phenol derivatives, processes for their preparation and pharmaceutical compositions containing them | GLAXO GROUP LIMITED (GB) | 1981-05-06 | — | — | EP | disclosed |