Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3067735 | 0.83 | TSHR (0.37) | L3MBTL1TP53TDP1POLBSMN1; SMN2 | |
| SCHEMBL15855878 | 0.81 | L3MBTL1 (0.53) | L3MBTL1TP53TDP1POLBSMN1; SMN2 | |
| SCHEMBL2223238 | 0.79 | TP53 (0.54) | L3MBTL1TP53TDP1POLBSMN1; SMN2 | |
| SCHEMBL2641107 | 0.79 | L3MBTL1 (0.51) | L3MBTL1TP53TDP1POLBSMN1; SMN2 | |
| SCHEMBL7823777 | 0.79 | L3MBTL1 (0.51) | L3MBTL1TP53TDP1POLBSMN1; SMN2 | |
| SCHEMBL27175921 | 0.79 | L3MBTL1 (0.51) | L3MBTL1TP53TDP1POLBSMN1; SMN2 | |
| SCHEMBL28415213 | 0.78 | L3MBTL1 (0.50) | L3MBTL1TP53TDP1POLBSMN1; SMN2 | |
| SCHEMBL13402295 | 0.78 | L3MBTL1 (0.50) | L3MBTL1TP53TDP1POLBSMN1; SMN2 | |
| SCHEMBL3823759 | 0.77 | HSD17B10 (0.44) | L3MBTL1TP53TDP1POLBHSD17B10 | |
| SCHEMBL545877 | 0.75 | TP53 (0.50) | L3MBTL1TP53TDP1POLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0002010-B1 | DERIVATIVES OF 2-IMINO-IMIDAZOLIDINE, PROCESSES FOR THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND INTERMEDIATES | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1982-07-14 | — | — | EP | disclosed |
| US-4282246-A | Antidiabetic furancarboxylic and thiphenecarboxylic acids | PFIZER INC. (US) | 1981-08-04 | — | — | US | disclosed |
| EP-0002010-A1 | Derivatives of 2-imino-imidazolidine, processes for their preparation, pharmaceutical compositions containing them and intermediates | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1979-05-30 | — | — | EP | disclosed |